Literature DB >> 19809596

Compact integration factor methods in high spatial dimensions.

Qing Nie1, Frederic Y M Wan, Yong-Tao Zhang, Xin-Feng Liu.   

Abstract

The dominant cost for integration factor (IF) or exponential time differencing (ETD) methods is the repeated vector-matrix multiplications involving exponentials of discretization matrices of differential operators. Although the discretization matrices usually are sparse, their exponentials are not, unless the discretization matrices are diagonal. For example, a two-dimensional system of N × N spatial points, the exponential matrix is of a size of N(2) × N(2) based on direct representations. The vector-matrix multiplication is of O(N(4)), and the storage of such matrix is usually prohibitive even for a moderate size N. In this paper, we introduce a compact representation of the discretized differential operators for the IF and ETD methods in both two- and three-dimensions. In this approach, the storage and CPU cost are significantly reduced for both IF and ETD methods such that the use of this type of methods becomes possible and attractive for two- or three-dimensional systems. For the case of two-dimensional systems, the required storage and CPU cost are reduced to O(N(2)) and O(N(3)), respectively. The improvement on three-dimensional systems is even more significant. We analyze and apply this technique to a class of semi-implicit integration factor method recently developed for stiff reaction-diffusion equations. Direct simulations on test equations along with applications to a morphogen system in two-dimensions and an intra-cellular signaling system in three-dimensions demonstrate an excellent efficiency of the new approach.

Year:  2008        PMID: 19809596      PMCID: PMC2756762          DOI: 10.1016/j.jcp.2008.01.050

Source DB:  PubMed          Journal:  J Comput Phys        ISSN: 0021-9991            Impact factor:   3.553


  19 in total

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Review 2.  Morphogen gradient interpretation.

Authors:  J B Gurdon; P Y Bourillot
Journal:  Nature       Date:  2001-10-25       Impact factor: 49.962

3.  Do morphogen gradients arise by diffusion?

Authors:  Arthur D Lander; Qing Nie; Frederic Y M Wan
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4.  Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms.

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Journal:  Science       Date:  2003-01-02       Impact factor: 47.728

5.  The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells.

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Journal:  Mol Cell Biol       Date:  2004-05       Impact factor: 4.272

Review 6.  AKAP signalling complexes: focal points in space and time.

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Journal:  Nat Rev Mol Cell Biol       Date:  2004-12       Impact factor: 94.444

Review 7.  Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals.

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Journal:  Trends Biochem Sci       Date:  1998-12       Impact factor: 13.807

8.  Local inhibition and long-range enhancement of Dpp signal transduction by Sog.

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Journal:  Nature       Date:  1999-04-01       Impact factor: 49.962

9.  A cytoplasmic inhibitor of the JNK signal transduction pathway.

Authors:  M Dickens; J S Rogers; J Cavanagh; A Raitano; Z Xia; J R Halpern; M E Greenberg; C L Sawyers; R J Davis
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10.  Localized Ectopic Expression of Dpp Receptors in a Drosophila Embryo.

Authors:  A D Lander; Q Nie; F Y M Wan; Y-T Zhang
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  9 in total

1.  A Robust and Efficient Method for Steady State Patterns in Reaction-Diffusion Systems.

Authors:  Wing-Cheong Lo; Long Chen; Ming Wang; Qing Nie
Journal:  J Comput Phys       Date:  2012-06-01       Impact factor: 3.553

2.  An Integration Factor Method for Stochastic and Stiff Reaction-Diffusion Systems.

Authors:  Catherine Ta; Dongyong Wang; Qing Nie
Journal:  J Comput Phys       Date:  2015-08-15       Impact factor: 3.553

3.  Semi-implicit Integration Factor Methods on Sparse Grids for High-Dimensional Systems.

Authors:  Dongyong Wang; Weitao Chen; Qing Nie
Journal:  J Comput Phys       Date:  2015-07-01       Impact factor: 3.553

4.  Array-representation Integration Factor Method for High-dimensional Systems.

Authors:  Dongyong Wang; Lei Zhang; Qing Nie
Journal:  J Comput Phys       Date:  2014-02-01       Impact factor: 3.553

5.  EXPONENTIAL TIME DIFFERENCING FOR HODGKIN-HUXLEY-LIKE ODES.

Authors:  Christoph Börgers; Alexander R Nectow
Journal:  SIAM J Sci Comput       Date:  2013       Impact factor: 2.373

6.  Operator Splitting Implicit Integration Factor Methods for Stiff Reaction-Diffusion-Advection Systems.

Authors:  Su Zhao; Jeremy Ovadia; Xinfeng Liu; Yong-Tao Zhang; Qing Nie
Journal:  J Comput Phys       Date:  2011-07       Impact factor: 3.553

7.  A HYBRID METHOD FOR STIFF REACTION-DIFFUSION EQUATIONS.

Authors:  Yuchi Qiu; Weitao Chen; Qing Nie
Journal:  Discrete Continuous Dyn Syst Ser B       Date:  2019-12       Impact factor: 1.327

8.  Compact integration factor methods for complex domains and adaptive mesh refinement.

Authors:  Xinfeng Liu; Qing Nie
Journal:  J Comput Phys       Date:  2010-08-10       Impact factor: 3.553

9.  Exponential Time Differencing Algorithm for Pulse-Coupled Hodgkin-Huxley Neural Networks.

Authors:  Zhong-Qi Kyle Tian; Douglas Zhou
Journal:  Front Comput Neurosci       Date:  2020-05-08       Impact factor: 2.380

  9 in total

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