Cost-effectiveness studies of diabetes prevention in high-risk patients.

The incidence of Type 2 diabetes is increasing annually. Impaired glucose tolerance has been described as a prediabetic state, which confers an increased risk of developing Type 2 diabetes along with its associated costly complications. Interventions targeted at individuals with impaired glucose tolerance can delay or prevent the onset of Type 2 diabetes. Several recent studies have shown that the incidence of Type 2 diabetes is reduced by lifestyle changes or pharmacological interventions. A literature search for studies investigating the costs and cost-effectiveness of diabetes prevention was performed, and the results summarized in this review. The limited health economic evidence currently published suggests that financial concerns should not be a barrier to the implementation of diabetes prevention strategies.