| Literature DB >> 19805565 |
Qiwen Yang1, Hui Wang, Hongli Sun, Hongbin Chen, Yingchun Xu, Minjun Chen.
Abstract
The resistance mechanism of 49 Enterobacteriaceae isolates with decreased susceptibility to carbapenems collected from 2004 to 2008 at 16 teaching hospitals in China was investigated. Moderate- to high-level carbapenem resistance in most isolates was more closely associated with loss or decreased expression of both major porins combined with production of AmpC or extended-spectrum beta-lactamase enzymes, while KPC-2, IMP-4, and IMP-8 carbapenemase production may lead to a low to moderate level of carbapenem resistance in Enterobacteriaceae in China.Entities:
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Year: 2009 PMID: 19805565 PMCID: PMC2798477 DOI: 10.1128/AAC.01099-09
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191