Literature DB >> 19805444

Selective inference in complex research.

Yoav Benjamini1, Ruth Heller, Daniel Yekutieli.   

Abstract

We explain the problem of selective inference in complex research using a recently published study: a replicability study of the associations in order to reveal and establish risk loci for type 2 diabetes. The false discovery rate approach to such problems will be reviewed, and we further address two problems: (i) setting confidence intervals on the size of the risk at the selected locations and (ii) selecting the replicable results.

Entities:  

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Year:  2009        PMID: 19805444      PMCID: PMC3263782          DOI: 10.1098/rsta.2009.0127

Source DB:  PubMed          Journal:  Philos Trans A Math Phys Eng Sci        ISSN: 1364-503X            Impact factor:   4.226


  6 in total

1.  Quantitative trait Loci analysis using the false discovery rate.

Authors:  Yoav Benjamini; Daniel Yekutieli
Journal:  Genetics       Date:  2005-06-14       Impact factor: 4.562

2.  Associating quantitative behavioral traits with gene expression in the brain: searching for diamonds in the hay.

Authors:  Anat Reiner-Benaim; Daniel Yekutieli; Noah E Letwin; Gregory I Elmer; Norman H Lee; Neri Kafkafi; Yoav Benjamini
Journal:  Bioinformatics       Date:  2007-09-07       Impact factor: 6.937

3.  FDR control by the BH procedure for two-sided correlated tests with implications to gene expression data analysis.

Authors:  Anat Reiner-Benaim
Journal:  Biom J       Date:  2007-02       Impact factor: 2.207

4.  Screening for partial conjunction hypotheses.

Authors:  Yoav Benjamini; Ruth Heller
Journal:  Biometrics       Date:  2008-02-06       Impact factor: 2.571

5.  A flexible two-stage procedure for identifying gene sets that are differentially expressed.

Authors:  Ruth Heller; Elisabetta Manduchi; Gregory R Grant; Warren J Ewens
Journal:  Bioinformatics       Date:  2009-02-11       Impact factor: 6.937

6.  Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.

Authors:  Eleftheria Zeggini; Michael N Weedon; Cecilia M Lindgren; Timothy M Frayling; Katherine S Elliott; Hana Lango; Nicholas J Timpson; John R B Perry; Nigel W Rayner; Rachel M Freathy; Jeffrey C Barrett; Beverley Shields; Andrew P Morris; Sian Ellard; Christopher J Groves; Lorna W Harries; Jonathan L Marchini; Katharine R Owen; Beatrice Knight; Lon R Cardon; Mark Walker; Graham A Hitman; Andrew D Morris; Alex S F Doney; Mark I McCarthy; Andrew T Hattersley
Journal:  Science       Date:  2007-04-26       Impact factor: 47.728

  6 in total
  30 in total

1.  Statistical challenges of high-dimensional data.

Authors:  Iain M Johnstone; D Michael Titterington
Journal:  Philos Trans A Math Phys Eng Sci       Date:  2009-11-13       Impact factor: 4.226

2.  Hierarchical topological network analysis of anatomical human brain connectivity and differences related to sex and kinship.

Authors:  Julio M Duarte-Carvajalino; Neda Jahanshad; Christophe Lenglet; Katie L McMahon; Greig I de Zubicaray; Nicholas G Martin; Margaret J Wright; Paul M Thompson; Guillermo Sapiro
Journal:  Neuroimage       Date:  2011-11-12       Impact factor: 6.556

3.  Weighted False Discovery Rate Control in Large-Scale Multiple Testing.

Authors:  Pallavi Basu; T Tony Cai; Kiranmoy Das; Wenguang Sun
Journal:  J Am Stat Assoc       Date:  2018-06-12       Impact factor: 5.033

4.  Identification of subgroups with differential treatment effects for longitudinal and multiresponse variables.

Authors:  Wei-Yin Loh; Haoda Fu; Michael Man; Victoria Champion; Menggang Yu
Journal:  Stat Med       Date:  2016-06-27       Impact factor: 2.373

5.  Exact statistical tests for the intersection of independent lists of genes.

Authors:  Loki Natarajan; Minya Pu; Karen Messer
Journal:  Ann Appl Stat       Date:  2012-06       Impact factor: 2.083

6.  Opposing effects of oxytocin on overt compliance and lasting changes to memory.

Authors:  Micah G Edelson; Maya Shemesh; Abraham Weizman; Shahak Yariv; Tali Sharot; Yadin Dudai
Journal:  Neuropsychopharmacology       Date:  2014-09-13       Impact factor: 7.853

7.  Deciding whether follow-up studies have replicated findings in a preliminary large-scale omics study.

Authors:  Ruth Heller; Marina Bogomolov; Yoav Benjamini
Journal:  Proc Natl Acad Sci U S A       Date:  2014-11-03       Impact factor: 11.205

8.  A randomized-controlled trial comparing supervised aerobic training to resistance training followed by unsupervised exercise on physical functioning in older breast cancer survivors.

Authors:  Kerri M Winters-Stone; Britta Torgrimson-Ojerio; Nathan F Dieckmann; Sydnee Stoyles; Zahi Mitri; Shiuh-Wen Luoh
Journal:  J Geriatr Oncol       Date:  2021-08-21       Impact factor: 3.599

9.  Allele-biased expression in differentiating human neurons: implications for neuropsychiatric disorders.

Authors:  Mingyan Lin; Anastasia Hrabovsky; Erika Pedrosa; Tao Wang; Deyou Zheng; Herbert M Lachman
Journal:  PLoS One       Date:  2012-08-30       Impact factor: 3.240

10.  Five linkage regions each harbor multiple type 2 diabetes genes in the African American subset of the GENNID Study.

Authors:  Sandra J Hasstedt; Heather M Highland; Steven C Elbein; Craig L Hanis; Swapan K Das
Journal:  J Hum Genet       Date:  2013-04-04       Impact factor: 3.172

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