Literature DB >> 19803713

Geographic HIV type 1 subtype distribution in Rakai district, Uganda.

Aleisha N Collinson-Streng1, Andrew D Redd, Nelson K Sewankambo, David Serwadda, Mona Rezapour, Susanna L Lamers, Ronald H Gray, Maria J Wawer, Thomas C Quinn, Oliver Laeyendecker.   

Abstract

To analyze HIV-1 subtype distribution, sequence analysis was performed on serum specimens obtained in 1994 from the Rakai Health Sciences community cohort in Uganda. Portions of gag-p24 and env-gp41 were sequenced and HIV subtype was determined for 773 subjects residing in 10 community clusters in rural Uganda. Subtypes A (17%) and D (70%) were the most common strains in the population. Subtype distribution varied by geographic region with significantly more subtype A in northern community clusters compared with southern clusters (21% vs. 8%, p < 0.001) and more subtype D in southern clusters compared with northern clusters (78% vs. 65%, p < 0.008). These data illustrate the geographic complexity of subtype variation, which has important implications for HIV-1 vaccine design.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19803713      PMCID： PMC2785855          DOI： 10.1089/aid.2009.0127

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  14 in total

1.  Predominance of HIV type 1 subtype G among commercial sex workers from Kinshasa, Democratic Republic of Congo.

Authors:  C Yang; B Dash; S L Hanna; H S Frances; N Nzilambi; R C Colebunders; M St Louis; T C Quinn; T M Folks; R B Lal
Journal:  AIDS Res Hum Retroviruses       Date:  2001-03-01       Impact factor: 2.205

Review 2.  Genetic diversity of HIV-1: the moving target.

Authors:  M Peeters; P M Sharp
Journal:  AIDS       Date:  2000       Impact factor: 4.177

3.  Inter- and intra-genic intersubtype HIV-1 recombination in rural and semi-urban Uganda.

Authors:  David L Yirrell; Pontiano Kaleebu; Dilys Morgan; Christine Watera; Brian Magambo; Frederick Lyagoba; James Whitworth
Journal:  AIDS       Date:  2002-01-25       Impact factor: 4.177

4.  Detection of diverse variants of human immunodeficiency virus-1 groups M, N, and O and simian immunodeficiency viruses from chimpanzees by using generic pol and env primer pairs.

Authors:  C Yang; B C Dash; F Simon; G van der Groen; D Pieniazek; F Gao; B H Hahn; R B Lal
Journal:  J Infect Dis       Date:  2000-05-15       Impact factor: 5.226

5.  Slim disease: a new disease in Uganda and its association with HTLV-III infection.

Authors:  D Serwadda; R D Mugerwa; N K Sewankambo; A Lwegaba; J W Carswell; G B Kirya; A C Bayley; R G Downing; R S Tedder; S A Clayden; R A Weiss; A G Dalgleish
Journal:  Lancet       Date:  1985-10-19       Impact factor: 79.321

6.  Quantitative analysis of HIV-1 variants with the K103N resistance mutation after single-dose nevirapine in women with HIV-1 subtypes A, C, and D.

Authors:  Tamara S Flys; Shu Chen; Dana C Jones; Donald R Hoover; Jessica D Church; Susan A Fiscus; Anthony Mwatha; Laura A Guay; Francis Mmiro; Philippa Musoke; Newton Kumwenda; Taha E Taha; J Brooks Jackson; Susan H Eshleman
Journal:  J Acquir Immune Defic Syndr       Date:  2006-08-15       Impact factor: 3.731

7.  Effect of human immunodeficiency virus (HIV) type 1 envelope subtypes A and D on disease progression in a large cohort of HIV-1-positive persons in Uganda.

Authors:  Pontiano Kaleebu; Neil French; Cedric Mahe; David Yirrell; Christine Watera; Fred Lyagoba; Jessica Nakiyingi; Alleluiah Rutebemberwa; Dilys Morgan; Jonathan Weber; Charles Gilks; Jimmy Whitworth
Journal:  J Infect Dis       Date:  2002-04-16       Impact factor: 5.226

8.  Spatial phylodynamics of HIV-1 epidemic emergence in east Africa.

Authors:  Rebecca R Gray; Andrew J Tatem; Susanna Lamers; Wei Hou; Oliver Laeyendecker; David Serwadda; Nelson Sewankambo; Ronald H Gray; Maria Wawer; Thomas C Quinn; Maureen M Goodenow; Marco Salemi
Journal:  AIDS       Date:  2009-09-10       Impact factor: 4.177

9.  Knowledge about vaccines and willingness to participate in preventive HIV vaccine trials: a population-based study, Rakai, Uganda.

Authors:  Noah Kiwanuka; Merlin Robb; Godfrey Kigozi; Deborah Birx; James Philips; Fred Wabwire-Mangen; Maria J Wawer; Fred Nalugoda; Nelson K Sewankambo; David Serwadda; Ronald H Gray
Journal:  J Acquir Immune Defic Syndr       Date:  2004-06-01       Impact factor: 3.731

10.  Predominance of HIV-1 subtype A and D infections in Uganda.

Authors:  D J Hu; J Baggs; R G Downing; D Pieniazek; J Dorn; C Fridlund; B Biryahwaho; S D Sempala; M A Rayfield; T J Dondero; R Lal
Journal:  Emerg Infect Dis       Date:  2000 Nov-Dec       Impact factor: 6.883
View more
  17 in total

1.  Changes in the distribution of HIV type 1 subtypes D and A in Rakai District, Uganda between 1994 and 2002.

Authors:  Samantha A Conroy; Oliver Laeyendecker; Andrew D Redd; Aleisha Collinson-Streng; Xiangrong Kong; Fredrick Makumbi; Tom Lutalo; Nelson Sewankambo; Noah Kiwanuka; Ronald H Gray; Maria J Wawer; David Serwadda; Thomas C Quinn
Journal:  AIDS Res Hum Retroviruses       Date:  2010-10-06       Impact factor: 2.205

2.  Impact of HIV subtype on performance of the limiting antigen-avidity enzyme immunoassay, the bio-rad avidity assay, and the BED capture immunoassay in Rakai, Uganda.

Authors:  Andrew F Longosz; David Serwadda; Fred Nalugoda; Godfrey Kigozi; Veronica Franco; Ronald H Gray; Thomas C Quinn; Susan H Eshleman; Oliver Laeyendecker
Journal:  AIDS Res Hum Retroviruses       Date:  2013-10-25       Impact factor: 2.205

3.  Identification of HIV superinfection in seroconcordant couples in Rakai, Uganda, by use of next-generation deep sequencing.

Authors:  Andrew D Redd; Aleisha Collinson-Streng; Craig Martens; Stacy Ricklefs; Caroline E Mullis; Jordyn Manucci; Aaron A R Tobian; Ethan J Selig; Oliver Laeyendecker; Nelson Sewankambo; Ronald H Gray; David Serwadda; Maria J Wawer; Stephen F Porcella; Thomas C Quinn
Journal:  J Clin Microbiol       Date:  2011-06-22       Impact factor: 5.948

4.  Reconstruction of the Genetic History and the Current Spread of HIV-1 Subtype A in Germany.

Authors:  Kirsten Hanke; Nuno Rodrigues Faria; Denise Kühnert; Kaveh Pouran Yousef; Andrea Hauser; Karolin Meixenberger; Alexandra Hofmann; Viviane Bremer; Barbara Bartmeyer; Oliver Pybus; Claudia Kücherer; Max von Kleist; Norbert Bannert
Journal:  J Virol       Date:  2019-05-29       Impact factor: 5.103

5.  HIV-1 Subtype Distribution and Diversity Over 18 Years in Rakai, Uganda.

Authors:  Susanna L Lamers; Rebecca Rose; Sissy Cross; Christopher W Rodriguez; Andrew D Redd; Thomas C Quinn; David Serwadda; Joseph Kagaayi; Godfrey Kigozi; Ronald Galiwango; Ronald H Gray; M Kate Grabowski; Oliver Laeyendecker
Journal:  AIDS Res Hum Retroviruses       Date:  2020-06       Impact factor: 2.205

6.  Efficiency of CCR5 coreceptor utilization by the HIV quasispecies increases over time, but is not associated with disease progression.

Authors:  Andrew D Redd; Oliver Laeyendecker; Xiangrong Kong; Noah Kiwanuka; Tom Lutalo; Wei Huang; Ronald H Gray; Maria J Wawer; David Serwadda; Susan H Eshleman; Thomas C Quinn
Journal:  AIDS Res Hum Retroviruses       Date:  2011-08-05       Impact factor: 2.205

7.  Previously transmitted HIV-1 strains are preferentially selected during subsequent sexual transmissions.

Authors:  Andrew D Redd; Aleisha N Collinson-Streng; Nikolaos Chatziandreou; Caroline E Mullis; Oliver Laeyendecker; Craig Martens; Stacy Ricklefs; Noah Kiwanuka; Phyu Hninn Nyein; Tom Lutalo; Mary K Grabowski; Xiangrong Kong; Jordyn Manucci; Nelson Sewankambo; Maria J Wawer; Ronald H Gray; Stephen F Porcella; Anthony S Fauci; Manish Sagar; David Serwadda; Thomas C Quinn
Journal:  J Infect Dis       Date:  2012-09-19       Impact factor: 5.226

8.  Continuous spread of HIV-1 subtypes D and CRF01_AE in France from 2003 to 2009.

Authors:  Denys Brand; Françoise Cazein; Florence Lot; Sylvie Brunet; Damien Thierry; Alain Moreau; Josiane Pillonel; Caroline Semaille; Francis Barin
Journal:  J Clin Microbiol       Date:  2012-05-02       Impact factor: 5.948

9.  Recombination Analysis of Near Full-Length HIV-1 Sequences and the Identification of a Potential New Circulating Recombinant Form from Rakai, Uganda.

Authors:  Adam A Capoferri; Susanna L Lamers; Mary Kate Grabowski; Rebecca Rose; Maria J Wawer; David Serwadda; Ronald H Gray; Thomas C Quinn; Godfrey Kigozi; Joseph Kagaayi; Oliver Laeyendecker
Journal:  AIDS Res Hum Retroviruses       Date:  2020-03-02       Impact factor: 2.205

10.  HIV-1 Sequence Data Coverage in Central East Africa from 1959 to 2013.

Authors:  Susanna L Lamers; Andrew E Barbier; Oliver Ratmann; Christophe Fraser; Rebecca Rose; Oliver Laeyendecker; Mary K Grabowski
Journal:  AIDS Res Hum Retroviruses       Date:  2016-08-02       Impact factor: 2.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.