Literature DB >> 19802991

The pharmacy of ceftazidime.

B L Richardson1, J D Woodford, G D Andrews.   

Abstract

The stability of ceftazidime for injection in the dry state and after reconstitution with water for injections was determined. Compatibility of ceftazidime for injection with lignocaine hydrochloride injection (1.0% w/v) and several commonly used intravenous fluids was tested, Ceftazidime for injection was found to be essentially stable in the dry state and may be stored at 25 degrees C. In solution, loss of potency occurs slowly; it was concluded that, if stored at room temperature, vials reconstituted with either water for injections or lignocaine hydrochloride injection (1-0% w/v) should be used within 6 h of preparation and dilute solutions in intravenous fluids should be used within 24 h of preparation (6 h for sodium bicarbonate solution).

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Year:  1981        PMID: 19802991     DOI: 10.1093/jac/8.suppl_b.233

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  3 in total

Review 1.  Systematic review of stability data pertaining to selected antibiotics used for extended infusions in outpatient parenteral antimicrobial therapy (OPAT) at standard room temperature and in warmer climates.

Authors:  Stephen John Perks; Cassie Lanskey; Niechole Robinson; Tilley Pain; Richard Franklin
Journal:  Eur J Hosp Pharm       Date:  2019-06-20

2.  [Comparative in vitro study of the antimicrobial activity of ceftazidime against clinical isolates].

Authors:  W Klietmann; J Focht; K Nösner
Journal:  Infection       Date:  1987       Impact factor: 3.553

Review 3.  Clinical pharmacokinetics of the third generation cephalosporins.

Authors:  L Balant; P Dayer; R Auckenthaler
Journal:  Clin Pharmacokinet       Date:  1985 Mar-Apr       Impact factor: 6.447

  3 in total

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