Ryan G McCaughey1, Cara Chlebicki, Brian J F Wong. 1. Beckman Laser Institute and Medical Clinic, University of California, Irvine, California 92612, USA. ryanmccaughey@hotmail.com
Abstract
BACKGROUND: Laser light is known to stimulate nerves. This study investigated alternative wavelengths for nerve stimulation. MATERIALS AND METHODS: The sciatic nerves of rats were irradiated with four different lasers-a Ho:YAG (2100 nm), a Yb:glass fiber laser (1495 nm) and diode lasers (1450 nm and 1540 nm). RESULTS: All lasers evoked a visible leg twitch response, and electromyography confirmed muscle activation. The Yb:glass laser at 1495 nm delivered through a single mode fiber was found to be the most effective stimulus. The stimulation threshold for a 2 millisecond pulse from the Yb:glass laser was determined to be 3.7+/-2.8 mJ/cm(2). CONCLUSIONS: The Yb:glass laser has the potential for use in neurostimulation, as an alternative to electrical stimulation.
BACKGROUND: Laser light is known to stimulate nerves. This study investigated alternative wavelengths for nerve stimulation. MATERIALS AND METHODS: The sciatic nerves of rats were irradiated with four different lasers-a Ho:YAG (2100 nm), a Yb:glass fiber laser (1495 nm) and diode lasers (1450 nm and 1540 nm). RESULTS: All lasers evoked a visible leg twitch response, and electromyography confirmed muscle activation. The Yb:glass laser at 1495 nm delivered through a single mode fiber was found to be the most effective stimulus. The stimulation threshold for a 2 millisecond pulse from the Yb:glass laser was determined to be 3.7+/-2.8 mJ/cm(2). CONCLUSIONS: The Yb:glass laser has the potential for use in neurostimulation, as an alternative to electrical stimulation.
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