Literature DB >> 19802348

Drosophila melanogaster as a model system for genetics of postnatal cardiac function.

Matthew J Wolf1, Howard A Rockman.   

Abstract

The fruit fly, Drosophila melanogaster, is an excellent model system that has a vast set of molecular tools and mutants to dissect the genetic pathways that are responsible for the normal and abnormal cardiac function. While the majority of studies have focused on heart development in the Drosophila embryo, attention has recently focused on the structure and function of the adult fly heart as a model of human heart failure. Here we review strategies to identify novel genes and pathways that cause or modify dilated cardiomyopathy in adult Drosophila.

Entities:  

Year:  2008        PMID： 19802348      PMCID： PMC2753975          DOI： 10.1016/j.ddmod.2009.02.002

Source DB:  PubMed          Journal:  Drug Discov Today Dis Models        ISSN： 1740-6757


  44 in total

1.  One hundred years of high-throughput Drosophila research.

Authors:  Mathias Beller; Brian Oliver
Journal:  Chromosome Res       Date:  2006       Impact factor: 5.239

2.  Big, bad hearts: from flies to man.

Authors:  Fabrizio C Serluca; Mark C Fishman
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-06       Impact factor: 11.205

3.  Homophila: human disease gene cognates in Drosophila.

Authors:  Samson Chien; Lawrence T Reiter; Ethan Bier; Michael Gribskov
Journal:  Nucleic Acids Res       Date:  2002-01-01       Impact factor: 16.971

4.  Age-associated cardiac dysfunction in Drosophila melanogaster.

Authors:  G Paternostro; C Vignola; D U Bartsch; J H Omens; A D McCulloch; J C Reed
Journal:  Circ Res       Date:  2001-05-25       Impact factor: 17.367

5.  Morphology of the pupal heart, adult heart, and associated tissues in the fruit fly, Drosophila melanogaster.

Authors:  N J Curtis; J M Ringo; H B Dowse
Journal:  J Morphol       Date:  1999-06       Impact factor: 1.804

6.  Innervation of the heart of the adult fruit fly, Drosophila melanogaster.

Authors:  Davide Dulcis; Richard B Levine
Journal:  J Comp Neurol       Date:  2003-10-27       Impact factor: 3.215

7.  Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome.

Authors:  Annette L Parks; Kevin R Cook; Marcia Belvin; Nicholas A Dompe; Robert Fawcett; Kari Huppert; Lory R Tan; Christopher G Winter; Kevin P Bogart; Jennifer E Deal; Megan E Deal-Herr; Deanna Grant; Marie Marcinko; Wesley Y Miyazaki; Stephanie Robertson; Kenneth J Shaw; Mariano Tabios; Valentina Vysotskaia; Lora Zhao; Rachel S Andrade; Kyle A Edgar; Elizabeth Howie; Keith Killpack; Brett Milash; Amanda Norton; Doua Thao; Kellie Whittaker; Millicent A Winner; Lori Friedman; Jonathan Margolis; Matthew A Singer; Casey Kopczynski; Daniel Curtis; Thomas C Kaufman; Gregory D Plowman; Geoffrey Duyk; Helen L Francis-Lang
Journal:  Nat Genet       Date:  2004-02-22       Impact factor: 38.330

8.  The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes.

Authors:  Hugo J Bellen; Robert W Levis; Guochun Liao; Yuchun He; Joseph W Carlson; Garson Tsang; Martha Evans-Holm; P Robin Hiesinger; Karen L Schulze; Gerald M Rubin; Roger A Hoskins; Allan C Spradling
Journal:  Genetics       Date:  2004-06       Impact factor: 4.562

9.  Genetic variation for cardiac dysfunction in Drosophila.

Authors:  Karen A Ocorr; Timothy Crawley; Greg Gibson; Rolf Bodmer
Journal:  PLoS One       Date:  2007-07-11       Impact factor: 3.240

10.  Genetic and physiologic dissection of the vertebrate cardiac conduction system.

Authors:  Neil C Chi; Robin M Shaw; Benno Jungblut; Jan Huisken; Tania Ferrer; Rima Arnaout; Ian Scott; Dimitris Beis; Tong Xiao; Herwig Baier; Lily Y Jan; Martin Tristani-Firouzi; Didier Y R Stainier
Journal:  PLoS Biol       Date:  2008-05-13       Impact factor: 8.029
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  16 in total

1.  A method to measure myocardial calcium handling in adult Drosophila.

Authors:  Na Lin; Nima Badie; Lin Yu; Dennis Abraham; Heping Cheng; Nenad Bursac; Howard A Rockman; Matthew J Wolf
Journal:  Circ Res       Date:  2011-04-14       Impact factor: 17.367

2.  A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in Drosophila.

Authors:  Madhulika Achal; Adriana S Trujillo; Girish C Melkani; Gerrie P Farman; Karen Ocorr; Meera C Viswanathan; Gaurav Kaushik; Christopher S Newhard; Bernadette M Glasheen; Anju Melkani; Jennifer A Suggs; Jeffrey R Moore; Douglas M Swank; Rolf Bodmer; Anthony Cammarato; Sanford I Bernstein
Journal:  J Mol Biol       Date:  2016-04-20       Impact factor: 5.469

Review 3.  Time-Restricted Eating to Prevent and Manage Chronic Metabolic Diseases.

Authors:  Amandine Chaix; Emily N C Manoogian; Girish C Melkani; Satchidananda Panda
Journal:  Annu Rev Nutr       Date:  2019-06-10       Impact factor: 11.848

Review 4.  Clinical considerations of heritable factors in common heart failure.

Authors:  Thomas P Cappola; Gerald W Dorn
Journal:  Circ Cardiovasc Genet       Date:  2011-12

Review 5.  Drosophila, genetic screens, and cardiac function.

Authors:  Matthew J Wolf; Howard A Rockman
Journal:  Circ Res       Date:  2011-09-16       Impact factor: 17.367

6.  Cardiac responses to hypoxia and reoxygenation in Drosophila.

Authors:  Rachel Zarndt; Sarah Piloto; Frank L Powell; Gabriel G Haddad; Rolf Bodmer; Karen Ocorr
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2015-09-16       Impact factor: 3.619

Review 7.  Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery.

Authors:  Udai Bhan Pandey; Charles D Nichols
Journal:  Pharmacol Rev       Date:  2011-03-17       Impact factor: 25.468

8.  Reengineering a transmembrane protein to treat muscular dystrophy using exon skipping.

Authors:  Quan Q Gao; Eugene Wyatt; Jeff A Goldstein; Peter LoPresti; Lisa M Castillo; Alec Gazda; Natalie Petrossian; Judy U Earley; Michele Hadhazy; David Y Barefield; Alexis R Demonbreun; Carsten Bönnemann; Matthew Wolf; Elizabeth M McNally
Journal:  J Clin Invest       Date:  2015-10-12       Impact factor: 14.808

9.  Model system identification of novel congenital heart disease gene candidates: focus on RPL13.

Authors:  Analyne M Schroeder; Massoud Allahyari; Georg Vogler; Maria A Missinato; Tanja Nielsen; Michael S Yu; Jeanne L Theis; Lars A Larsen; Preeya Goyal; Jill A Rosenfeld; Timothy J Nelson; Timothy M Olson; Alexandre R Colas; Paul Grossfeld; Rolf Bodmer
Journal:  Hum Mol Genet       Date:  2019-12-01       Impact factor: 6.150

Review 10.  Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction.

Authors:  Gaurav Kaushik; Alexander C Zambon; Alexander Fuhrmann; Sanford I Bernstein; Rolf Bodmer; Adam J Engler; Anthony Cammarato
Journal:  J Cell Mol Med       Date:  2012-08       Impact factor: 5.310
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