Literature DB >> 19799418

Vitamin B(12) and redox homeostasis: cob(II)alamin reacts with superoxide at rates approaching superoxide dismutase (SOD).

Edward Suarez-Moreira1, June Yun, Catherine S Birch, John H H Williams, Andrew McCaddon, Nicola E Brasch.   

Abstract

We report a kinetic study of the reaction between superoxide and an important intracellular form of vitamin B(12), cob(II)alamin. Superoxide is implicated in the pathophysiology of many inflammatory diseases, whereas vitamin B(12) derivatives are often beneficial in their treatment. We found that cob(II)alamin reacts with superoxide at rates approaching those of superoxide dismutase itself, suggesting a probable mechanism by which vitamin B(12) protects against chronic inflammation and modulates redox homeostasis.

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Year:  2009        PMID： 19799418     DOI： 10.1021/ja904670x

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  34 in total

1.  The reaction of HOCl and cyanocobalamin: corrin destruction and the liberation of cyanogen chloride.

Authors:  Husam M Abu-Soud; Dhiman Maitra; Jaeman Byun; Carlos Eduardo A Souza; Jashoman Banerjee; Ghassan M Saed; Michael P Diamond; Peter R Andreana; Subramaniam Pennathur
Journal:  Free Radic Biol Med       Date:  2011-11-10       Impact factor: 7.376

2.  Kinetics and mechanism of oxidation of super-reduced cobalamin and cobinamide species by thiosulfate, sulfite and dithionite.

Authors:  Ilia A Dereven'kov; Denis S Salnikov; Sergei V Makarov; Gerry R Boss; Oskar I Koifman
Journal:  Dalton Trans       Date:  2013-11-21       Impact factor: 4.390

3.  Functional cobalamin (vitamin B12) deficiency: role of advanced age and disorders associated with increased oxidative stress.

Authors:  L R Solomon
Journal:  Eur J Clin Nutr       Date:  2015-01-07       Impact factor: 4.016

4.  Coordination chemistry controls the thiol oxidase activity of the B12-trafficking protein CblC.

Authors:  Zhu Li; Aranganathan Shanmuganathan; Markus Ruetz; Kazuhiro Yamada; Nicholas A Lesniak; Bernhard Kräutler; Thomas C Brunold; Markos Koutmos; Ruma Banerjee
Journal:  J Biol Chem       Date:  2017-04-25       Impact factor: 5.157

5.  Vitamin B12 protects against superoxide-induced cell injury in human aortic endothelial cells.

Authors:  Edward S Moreira; Nicola E Brasch; June Yun
Journal:  Free Radic Biol Med       Date:  2011-06-02       Impact factor: 7.376

6.  Comparative studies of reaction of cobalamin (II) and cobinamide (II) with sulfur dioxide.

Authors:  Ilia A Dereven'kov; Pavel A Ivlev; Cristina Bischin; Denis S Salnikov; Radu Silaghi-Dumitrescu; Sergei V Makarov; Oscar I Koifman
Journal:  J Biol Inorg Chem       Date:  2017-06-15       Impact factor: 3.358

7.  Mechanistic Studies on the Reaction of Nitrocobalamin with Glutathione: Kinetic evidence for formation of an aquacobalamin intermediate.

Authors:  David T Walker; Rohan S Dassanayake; Kamille A Garcia; Riya Mukherjee; Nicola E Brasch
Journal:  Eur J Inorg Chem       Date:  2013-06-01       Impact factor: 2.524

8.  The human B12 trafficking protein CblC processes nitrocobalamin.

Authors:  Romila Mascarenhas; Zhu Li; Carmen Gherasim; Markus Ruetz; Ruma Banerjee
Journal:  J Biol Chem       Date:  2020-05-26       Impact factor: 5.157

9.  Cobalamin-Associated Superoxide Scavenging in Neuronal Cells Is a Potential Mechanism for Vitamin B12-Deprivation Optic Neuropathy.

Authors:  Wesley Chan; Mohammadali Almasieh; Maria-Magdalena Catrinescu; Leonard A Levin
Journal:  Am J Pathol       Date:  2017-10-14       Impact factor: 4.307

10.  Pulse radiolysis studies on the reaction of the reduced vitamin B₁₂ complex Cob(II)alamin with superoxide.

Authors:  Rohan S Dassanayake; Diane E Cabelli; Nicola E Brasch
Journal:  Chembiochem       Date:  2013-05-13       Impact factor: 3.164
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