Literature DB >> 19795971

Pus and free bone flaps.

Lars Widdel1, Ken R Winston.   

Abstract

OBJECT: The goal of this investigation is to describe the results of a vigorous attempt to preserve contaminated free bone flaps and avoid the problems associated with the traditional and common practice of discarding the flap, administering a course of antibiotics, and after several months, performing a cranioplasty.
METHODS: Patients with clearly contaminated, free cranial bone flaps, including so-called high risk cases, were treated by meticulous debridement of the surgical bed, scrubbing, soaking, and then replacing the bone flap in its normal position, and administering a course of intravenous antibiotics.
RESULTS: Fourteen patients with contaminated avascular cranial bone flaps were treated using this technique. All bone flaps were able to be preserved. Conclusions Patients with bacteriologically contaminated, free bone flaps can be treated successfully without discarding the flaps. Success is dependent upon aggressive surgical debridement and persistence.

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Year:  2009        PMID: 19795971     DOI: 10.3171/2009.5.PEDS0963

Source DB:  PubMed          Journal:  J Neurosurg Pediatr        ISSN: 1933-0707            Impact factor:   2.375


  6 in total

1.  Bone flap salvage in acute surgical site infection after craniotomy for tumor resection.

Authors:  David J Wallace; Michael J McGinity; John R Floyd
Journal:  Neurosurg Rev       Date:  2018-02-10       Impact factor: 3.042

2.  3D Bioprinted Scaffolds Containing Viable Macrophages and Antibiotics Promote Clearance of Staphylococcus aureus Craniotomy-Associated Biofilm Infection.

Authors:  Amy Aldrich; Mitchell A Kuss; Bin Duan; Tammy Kielian
Journal:  ACS Appl Mater Interfaces       Date:  2019-03-21       Impact factor: 9.229

3.  Early versus delayed debridement for surgical site infection after oncological neurosurgery.

Authors:  Joao Paulo Mota Telles; Vitor Nagai Yamaki; Ricardo Andrade Caracante; Victor Hugo Barboza Martins; Wellingson Silva Paiva; Manoel Jacobsen Teixeira; Eberval Gadelha Figueiredo; Iuri Santana Neville
Journal:  Surg Neurol Int       Date:  2022-07-01

4.  Prefabricated patient-matched cranial implants for reconstruction of large skull defects.

Authors:  Jarle Sundseth; Jon Berg-Johnsen
Journal:  J Cent Nerv Syst Dis       Date:  2013-02-20

5.  Gram-negative Cranial Bone Flap Infection Treated with Continuous Gentamicin Irrigation: A Case Report.

Authors:  Jamie Toms; Lisa Kurczewski; Robert Simonds; R Scott Graham; Jason Harrison
Journal:  Cureus       Date:  2019-03-20

Review 6.  Immunopathogenesis of Craniotomy Infection and Niche-Specific Immune Responses to Biofilm.

Authors:  Sharon Db de Morais; Gunjan Kak; Joseph P Menousek; Tammy Kielian
Journal:  Front Immunol       Date:  2021-02-23       Impact factor: 7.561

  6 in total

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