BACKGROUND: Optimizing cerebral oxygenation is advocated to improve outcome in head-injured patients. The purpose of this study was to compare outcomes in brain-injured patients treated with 2 types of monitors. METHODS: Patients with traumatic brain injury and a Glasgow Coma Scale score<8 were identified on admission. A polarographic cerebral oxygen/pressure monitor (Licox) or fiberoptic intracranial pressure monitor (Camino) was inserted. An evidence-based algorithm for treatment was implemented. Elements from the prehospital and emergency department records and the first 10 days of intensive care unit (ICU) care were collected. Glasgow Outcome Scores (GOS) were determined every 3 months after discharge. RESULTS: Over a 3-year period, 145 patients were entered into the study; 81 patients in the Licox group and 64 patients in the Camino group. Mortality, hospital length of stay, and ICU length of stay were equivalent in the 2 groups. More patients in the Licox group achieved a moderate/recovered GOS at 3 months than in the Camino Group (79% vs 61%; P = .09). CONCLUSION: Three-month GOS revealed a clinically meaningful 18% benefit in patients undergoing cerebral oxygen monitoring and optimization. Six-month outcomes were also better. Unfortunately, these important differences did not reach significance. Continued study of the benefits of cerebral oxygen monitoring is warranted.
BACKGROUND: Optimizing cerebral oxygenation is advocated to improve outcome in head-injured patients. The purpose of this study was to compare outcomes in brain-injured patients treated with 2 types of monitors. METHODS:Patients with traumatic brain injury and a Glasgow Coma Scale score<8 were identified on admission. A polarographic cerebral oxygen/pressure monitor (Licox) or fiberoptic intracranial pressure monitor (Camino) was inserted. An evidence-based algorithm for treatment was implemented. Elements from the prehospital and emergency department records and the first 10 days of intensive care unit (ICU) care were collected. Glasgow Outcome Scores (GOS) were determined every 3 months after discharge. RESULTS: Over a 3-year period, 145 patients were entered into the study; 81 patients in the Licox group and 64 patients in the Camino group. Mortality, hospital length of stay, and ICU length of stay were equivalent in the 2 groups. More patients in the Licox group achieved a moderate/recovered GOS at 3 months than in the Camino Group (79% vs 61%; P = .09). CONCLUSION: Three-month GOS revealed a clinically meaningful 18% benefit in patients undergoing cerebral oxygen monitoring and optimization. Six-month outcomes were also better. Unfortunately, these important differences did not reach significance. Continued study of the benefits of cerebral oxygen monitoring is warranted.
Authors: Llewellyn C Padayachy; Ursula Rohlwink; Eugene Zwane; Graham Fieggen; Jonathan C Peter; Anthony A Figaji Journal: Childs Nerv Syst Date: 2012-06-17 Impact factor: 1.475
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Authors: Leif-Erik Bohman; Gregory G Heuer; Lukascz Macyszyn; Eileen Maloney-Wilensky; Suzanne Frangos; Peter D Le Roux; Andrew Kofke; Joshua M Levine; Michael F Stiefel Journal: Neurocrit Care Date: 2011-06 Impact factor: 3.210
Authors: Joel A Green; Daniela C Pellegrini; Wayne E Vanderkolk; Bryan E Figueroa; Evert A Eriksson Journal: Neurocrit Care Date: 2013-02 Impact factor: 3.210
Authors: K P Budohoski; C Zweifel; M Kasprowicz; E Sorrentino; J Diedler; K M Brady; P Smielewski; D K Menon; J D Pickard; P J Kirkpatrick; M Czosnyka Journal: Br J Anaesth Date: 2011-10-27 Impact factor: 9.166
Authors: Mioara D Manole; Patrick M Kochanek; Hülya Bayır; Henry Alexander; Cameron Dezfulian; Ericka L Fink; Michael J Bell; Robert S B Clark Journal: Pediatr Res Date: 2013-11-13 Impact factor: 3.756