Literature DB >> 19785437

Twenty-six years of anti-HIV drug discovery: where do we stand and where do we go?

Youcef Mehellou1, Erik De Clercq.   

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Year:  2010        PMID： 19785437     DOI： 10.1021/jm900492g

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  80 in total

1.  The Journey of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) from Lab to Clinic.

Authors:  Vigneshwaran Namasivayam; Murugesan Vanangamudi; Victor G Kramer; Sonali Kurup; Peng Zhan; Xinyong Liu; Jacob Kongsted; Siddappa N Byrareddy
Journal:  J Med Chem       Date:  2018-12-27       Impact factor: 7.446

Review 2.  Nitrile-containing pharmaceuticals: efficacious roles of the nitrile pharmacophore.

Authors:  Fraser F Fleming; Lihua Yao; P C Ravikumar; Lee Funk; Brian C Shook
Journal:  J Med Chem       Date:  2010-08-30       Impact factor: 7.446

3.  Microwave assisted organic synthesis (MAOS) of small molecules as potential HIV-1 integrase inhibitors.

Authors:  Stefania Ferro; Sara De Grazia; Laura De Luca; Rosaria Gitto; Caterina Elisa Faliti; Zeger Debyzer; Alba Chimirri
Journal:  Molecules       Date:  2011-08-11       Impact factor: 4.411

4.  Probing chelation motifs in HIV integrase inhibitors.

Authors:  Arpita Agrawal; Jamie DeSoto; Jessica L Fullagar; Kasthuraiah Maddali; Shahrzad Rostami; Douglas D Richman; Yves Pommier; Seth M Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-27       Impact factor: 11.205

5.  Double Variational Binding--(SMILES) Conformational Analysis by Docking Mechanisms for Anti-HIV Pyrimidine Ligands.

Authors:  Mihai V Putz; Nicoleta A Dudaș; Adriana Isvoran
Journal:  Int J Mol Sci       Date:  2015-08-18       Impact factor: 5.923

Review 6.  Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS.

Authors:  Arun K Ghosh; Heather L Osswald; Gary Prato
Journal:  J Med Chem       Date:  2016-01-22       Impact factor: 7.446

Review 7.  Identification of HIV inhibitors guided by free energy perturbation calculations.

Authors:  Orlando Acevedo; Zandrea Ambrose; Patrick T Flaherty; Hadega Aamer; Prashi Jain; Somisetti V Sambasivarao
Journal:  Curr Pharm Des       Date:  2012       Impact factor: 3.116

8.  6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach.

Authors:  Roberta Costi; Mathieu Métifiot; Francesca Esposito; Giuliana Cuzzucoli Crucitti; Luca Pescatori; Antonella Messore; Luigi Scipione; Silvano Tortorella; Luca Zinzula; Ettore Novellino; Yves Pommier; Enzo Tramontano; Christophe Marchand; Roberto Di Santo
Journal:  J Med Chem       Date:  2013-11-05       Impact factor: 7.446

9.  Room Temperature Neutron Crystallography of Drug Resistant HIV-1 Protease Uncovers Limitations of X-ray Structural Analysis at 100 K.

Authors:  Oksana Gerlits; David A Keen; Matthew P Blakeley; John M Louis; Irene T Weber; Andrey Kovalevsky
Journal:  J Med Chem       Date:  2017-02-28       Impact factor: 7.446

10.  Rapid genotyping using pyrene-perylene locked nucleic acid complexes.

Authors:  T Santhosh Kumar; Anna Myznikova; Evgeniya Samokhina; Irina Kira Astakhova
Journal:  Artif DNA PNA XNA       Date:  2013 Apr-Jun
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