| Literature DB >> 19782772 |
Xiaolei Qiu1, Katharine V Brown, Yehu Moran, Danica Chen.
Abstract
The beneficial effects of calorie restriction diet in extending lifespan and preventing diseases have long been recognized. Recent genetic and molecular studies in model organisms began to uncover the molecular regulation of calorie restriction response, with the gene SIR2 playing an essential role. This article summarizes the latest development on how mammalian SIR2 homologs coordinately regulate the calorie restriction response. Copyright 2009 Elsevier B.V. All rights reserved.Entities:
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Year: 2009 PMID： 19782772 DOI： 10.1016/j.bbapap.2009.09.015
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002