Literature DB >> 19781696

Improvement in quality-of-life questionnaire measures in obese adolescent females with polycystic ovary syndrome treated with lifestyle changes and oral contraceptives, with or without metformin.

Miranda Harris-Glocker1, Kristin Davidson, Lynda Kochman, David Guzick, Kathleen Hoeger.   

Abstract

We studied the effect of metformin or placebo in a lifestyle modification program combined with oral contraceptives (OC) on quality-of-life parameters measured by the polycystic ovary syndrome (PCOS) questionnaire in obese adolescent women with validated PCOS. The quality-of-life indicators were measured at baseline and conclusion for five domains on the PCOS questionnaire, with equal improvement in scores in both placebo and metformin groups, suggesting that the addition of metformin does not add improvement to quality-of-life measures above those observed with lifestyle modification and OC treatment. Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

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Year:  2009        PMID： 19781696      PMCID： PMC3756311          DOI： 10.1016/j.fertnstert.2009.08.006

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  15 in total

1.  Diagnosis, phenotype, and prevalence of polycystic ovary syndrome.

Authors:  Enrico Carmina; Ricardo Azziz
Journal:  Fertil Steril       Date:  2006-07       Impact factor: 7.329

2.  Effects of polycystic ovary syndrome on health-related quality of life.

Authors:  Krishna Upadhya; Maria Trent
Journal:  Expert Rev Pharmacoecon Outcomes Res       Date:  2007-12       Impact factor: 2.217

Review 3.  Polycystic ovary syndrome.

Authors:  S Franks
Journal:  N Engl J Med       Date:  1995-09-28       Impact factor: 91.245

Review 4.  The polycystic ovary syndrome.

Authors:  S S Yen
Journal:  Clin Endocrinol (Oxf)       Date:  1980-02       Impact factor: 3.478

5.  Obesity and lifestyle management in polycystic ovary syndrome.

Authors:  Kathleen M Hoeger
Journal:  Clin Obstet Gynecol       Date:  2007-03       Impact factor: 2.190

6.  Fertility concerns and sexual behavior in adolescent girls with polycystic ovary syndrome: implications for quality of life.

Authors:  Maria E Trent; Michael Rich; S Bryn Austin; Catherine M Gordon
Journal:  J Pediatr Adolesc Gynecol       Date:  2003-02       Impact factor: 1.814

7.  Development of a health-related quality-of-life questionnaire (PCOSQ) for women with polycystic ovary syndrome (PCOS).

Authors:  L Cronin; G Guyatt; L Griffith; E Wong; R Azziz; W Futterweit; D Cook; A Dunaif
Journal:  J Clin Endocrinol Metab       Date:  1998-06       Impact factor: 5.958

8.  Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002.

Authors:  Allison A Hedley; Cynthia L Ogden; Clifford L Johnson; Margaret D Carroll; Lester R Curtin; Katherine M Flegal
Journal:  JAMA       Date:  2004-06-16       Impact factor: 56.272

9.  [Determinants of health related quality of life in women with polycystic ovary syndrome].

Authors:  B Pekhlivanov; G Kolarov; S Kavŭrdzhikova; S Stoĭkov
Journal:  Akush Ginekol (Sofiia)       Date:  2006

10.  The Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (PCOSQ): a validation.

Authors:  G L Jones; K Benes; T L Clark; R Denham; M G Holder; T J Haynes; N C Mulgrew; K E Shepherd; V H Wilkinson; M Singh; A Balen; H Lashen; W L Ledger
Journal:  Hum Reprod       Date:  2004-02       Impact factor: 6.918
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  16 in total

1.  Contraception quandaries: oral contraceptive decisions in the pediatric endocrinology office.

Authors:  John S Fuqua; Emily K Sims
Journal:  J Clin Endocrinol Metab       Date:  2012-01       Impact factor: 5.958

2.  Anogenital distance in newborn daughters of women with polycystic ovary syndrome indicates fetal testosterone exposure.

Authors:  E S Barrett; K M Hoeger; S Sathyanarayana; D H Abbott; J B Redmon; R H N Nguyen; S H Swan
Journal:  J Dev Orig Health Dis       Date:  2018-01-09       Impact factor: 2.401

3.  Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: a pilot randomized double-blind study.

Authors:  Gwinnett Ladson; William C Dodson; Stephanie D Sweet; Anthony E Archibong; Allen R Kunselman; Laurence M Demers; Peter A Lee; Nancy I Williams; Ponjola Coney; Richard S Legro
Journal:  Fertil Steril       Date:  2011-06-30       Impact factor: 7.329

Review 4.  Depression and Anxiety in Polycystic Ovary Syndrome: Etiology and Treatment.

Authors:  Laura G Cooney; Anuja Dokras
Journal:  Curr Psychiatry Rep       Date:  2017-09-20       Impact factor: 5.285

5.  The Pregnancy in Polycystic Ovary Syndrome II study: baseline characteristics and effects of obesity from a multicenter randomized clinical trial.

Authors:  Richard S Legro; Robert G Brzyski; Michael P Diamond; Christos Coutifaris; William D Schlaff; Ruben Alvero; Peter Casson; Gregory M Christman; Hao Huang; Qingshang Yan; Daniel J Haisenleder; Kurt T Barnhart; G Wright Bates; Rebecca Usadi; Richard Lucidi; Valerie Baker; J C Trussell; Stephen A Krawetz; Peter Snyder; Dana Ohl; Nanette Santoro; Esther Eisenberg; Heping Zhang
Journal:  Fertil Steril       Date:  2013-10-21       Impact factor: 7.329

6.  Weight Loss and Lowering Androgens Predict Improvements in Health-Related Quality of Life in Women With PCOS.

Authors:  Anuja Dokras; David B Sarwer; Kelly C Allison; Lauren Milman; Penny M Kris-Etherton; Allen R Kunselman; Christy M Stetter; Nancy I Williams; Carol L Gnatuk; Stephanie J Estes; Jennifer Fleming; Christos Coutifaris; Richard S Legro
Journal:  J Clin Endocrinol Metab       Date:  2016-06-02       Impact factor: 5.958

7.  Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in polycystic ovary syndrome.

Authors:  Eloise Fraison; Elena Kostova; Lisa J Moran; Sophia Bilal; Carolyn C Ee; Christos Venetis; Michael F Costello
Journal:  Cochrane Database Syst Rev       Date:  2020-08-13

8.  Physical activity and mental health in women with polycystic ovary syndrome.

Authors:  Lauren K Banting; Melanie Gibson-Helm; Remco Polman; Helena J Teede; Nigel K Stepto
Journal:  BMC Womens Health       Date:  2014-03-27       Impact factor: 2.809

9.  Acupuncture and physical exercise for affective symptoms and health-related quality of life in polycystic ovary syndrome: secondary analysis from a randomized controlled trial.

Authors:  Elisabet Stener-Victorin; Göran Holm; Per Olof Janson; Deborah Gustafson; Margda Waern
Journal:  BMC Complement Altern Med       Date:  2013-06-13       Impact factor: 3.659

Review 10.  Complications and challenges associated with polycystic ovary syndrome: current perspectives.

Authors:  Stefano Palomba; Susanna Santagni; Angela Falbo; Giovanni Battista La Sala
Journal:  Int J Womens Health       Date:  2015-07-31
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