Literature DB >> 19779641

Discovery, biological activity, synthesis and potential therapeutic utility of naturally occurring histone deacetylase inhibitors.

Tenaya L Newkirk1, Albert A Bowers, Robert M Williams.   

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Year:  2009        PMID： 19779641     DOI： 10.1039/b817886k

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


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  21 in total

Review 1.  Macrocyclic histone deacetylase inhibitors.

Authors:  Sandra C Mwakwari; Vishal Patil; William Guerrant; Adegboyega K Oyelere
Journal:  Curr Top Med Chem       Date:  2010       Impact factor: 3.295

Review 2.  Discovery and mechanism of natural products as modulators of histone acetylation.

Authors:  Lilibeth A Salvador; Hendrik Luesch
Journal:  Curr Drug Targets       Date:  2012-07       Impact factor: 3.465

Review 3.  An overview of naturally occurring histone deacetylase inhibitors.

Authors:  Bumki Kim; Jiyong Hong
Journal:  Curr Top Med Chem       Date:  2015       Impact factor: 3.295

4.  Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole.

Authors:  Dane J Clausen; William B Smith; Brandon E Haines; Olaf Wiest; James E Bradner; Robert M Williams
Journal:  Bioorg Med Chem       Date:  2015-03-31       Impact factor: 3.641

5.  Trichostatin A inhibits deacetylation of histone H3 and p53 by SIRT6.

Authors:  Marci Wood; Stacia Rymarchyk; Song Zheng; Yana Cen
Journal:  Arch Biochem Biophys       Date:  2017-12-09       Impact factor: 4.013

6.  Discovery of a Novel HDAC2 Inhibitor by a Scaffold-Merging Hybrid Query.

Authors:  Nikita Basant; Xionghao Lin; Terry-Elinor Reid; Pradeep K Karla; Xiang S Wang
Journal:  Comb Chem High Throughput Screen       Date:  2015       Impact factor: 1.339

7.  Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.

Authors:  Yanxia Liu; Lilibeth A Salvador; Seongrim Byeon; Yongcheng Ying; Jason C Kwan; Brian K Law; Jiyong Hong; Hendrik Luesch
Journal:  J Pharmacol Exp Ther       Date:  2010-08-25       Impact factor: 4.030

Review 8.  Largazole: from discovery to broad-spectrum therapy.

Authors:  Jiyong Hong; Hendrik Luesch
Journal:  Nat Prod Rep       Date:  2012-02-14       Impact factor: 13.423

9.  Potent and orally efficacious bisthiazole-based histone deacetylase inhibitors.

Authors:  Fei Chen; Hui Chai; Ming-Bo Su; Yang-Ming Zhang; Jia Li; Xin Xie; Fa-Jun Nan
Journal:  ACS Med Chem Lett       Date:  2014-04-04       Impact factor: 4.345

10.  Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.

Authors:  Jennifer M Guerra-Bubb; Albert A Bowers; William B Smith; Ronald Paranal; Guillermina Estiu; Olaf Wiest; James E Bradner; Robert M Williams
Journal:  Bioorg Med Chem Lett       Date:  2013-06-18       Impact factor: 2.823
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