Literature DB >> 19773677

Gene polymorphism of IFNG +874 T/A and TLR4 +896 A/G and recurrent infections and wheezing in toddlers with history of bronchiolitis.

Kirsi Nuolivirta1, Mikko Hurme, Anne Halkosalo, Petri Koponen, Matti Korppi, Timo Vesikari, Merja Helminen.   

Abstract

Cytokine and TLR4 polymorphisms and their association with the infection history of 129 children hospitalized for bronchiolitis during the first 6 months of life were analyzed. The carriers of IFNG +874 T/A allele A had fewer infections and use of inhaled corticosteroids and the carriers of TLR4+896 A/G allele G were more likely to need tympanostomy than noncarriers.

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Year:  2009        PMID: 19773677     DOI: 10.1097/INF.0b013e3181af37ee

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN: 0891-3668            Impact factor:   2.129


  8 in total

1.  Genetic predisposition of RSV infection-related respiratory morbidity in preterm infants.

Authors:  Simon B Drysdale; Michael Prendergast; Mireia Alcazar; Theresa Wilson; Melvyn Smith; Mark Zuckerman; Simon Broughton; Gerrard F Rafferty; Sebastian L Johnston; Hennie M Hodemaekers; Riny Janssen; Louis Bont; Anne Greenough
Journal:  Eur J Pediatr       Date:  2014-02-02       Impact factor: 3.183

2.  Interleukin 1 receptor-like 1 rs13408661/13431828 polymorphism is associated with persistent post-bronchiolitis asthma at school age.

Authors:  Riikka Riikonen; Johanna Teräsjärvi; Eero Lauhkonen; Kirsi Nuolivirta; Qiushui He; Matti Korppi
Journal:  Acta Paediatr       Date:  2021-11-18       Impact factor: 4.056

3.  IL-10 Gene Polymorphisms Are Associated with Post-Bronchiolitis Lung Function Abnormalities at Six Years of Age.

Authors:  Eero Lauhkonen; Petri Koponen; Johanna Teräsjärvi; Kirsi Gröndahl-Yli-Hannuksela; Juho Vuononvirta; Kirsi Nuolivirta; Jyri O Toikka; Merja Helminen; Qiushui He; Matti Korppi
Journal:  PLoS One       Date:  2015-10-16       Impact factor: 3.240

4.  Post-bronchiolitis wheezing is associated with toll-like receptor 9 rs187084 gene polymorphism.

Authors:  Kirsi Nuolivirta; Sari Törmänen; Johanna Teräsjärvi; Juho Vuononvirta; Petri Koponen; Matti Korppi; Merja Helminen; Ville Peltola; Qiushui He
Journal:  Sci Rep       Date:  2016-08-08       Impact factor: 4.379

5.  TLR4 rs41426344 increases susceptibility of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in a central south Chinese Han population.

Authors:  Yan Wang; Lianghui Chen; Fang Li; Meihua Bao; Jie Zeng; Ju Xiang; Huaiqing Luo; Jianming Li; Liang Tang
Journal:  Pediatr Rheumatol Online J       Date:  2017-02-21       Impact factor: 3.054

6.  TLR5 rs5744174 gene polymorphism is associated with the virus etiology of infant bronchiolitis but not with post-bronchiolitis asthma.

Authors:  Sari Törmänen; Johanna Teräsjärvi; Eero Lauhkonen; Merja Helminen; Petri Koponen; Matti Korppi; Kirsi Nuolivirta; Qiushui He
Journal:  Health Sci Rep       Date:  2018-05-24

Review 7.  The role of TLR4 896 A>G and 1196 C>T in susceptibility to infections: a review and meta-analysis of genetic association studies.

Authors:  Panayiotis D Ziakas; Michael L Prodromou; Joseph El Khoury; Elias Zintzaras; Eleftherios Mylonakis
Journal:  PLoS One       Date:  2013-11-25       Impact factor: 3.240

8.  Gene Polymorphism of Toll-Like Receptors and Lung Function at Five to Seven Years of Age after Infant Bronchiolitis.

Authors:  Eero Lauhkonen; Petri Koponen; Juho Vuononvirta; Johanna Teräsjärvi; Kirsi Nuolivirta; Jyri O Toikka; Merja Helminen; Qiushui He; Matti Korppi
Journal:  PLoS One       Date:  2016-01-07       Impact factor: 3.240

  8 in total

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