Literature DB >> 1977246

Hypervariable regions of DNA for parentage testing and individual identification.

T Yokoi1, M Nata, T Odaira, K Sagisaka.   

Abstract

Four kinds of DNA probes that recognize hypervariable regions (HVR) were studied for parentage testing and individual identification. Allele frequencies and their confidence intervals among unrelated Japanese individuals were obtained. Codominant segregation of the polymorphism was confirmed in family studies. Two a priori probabilities were calculated for each HVR locus: the exclusion probabilities for an alleged father/mother/child trio and for an alleged parent/child duo, and the probabilities of matching of genotypes of two unrelated individuals or two siblings. The ease of availability of the probes and their highly discriminating polymorphic patterns mean they could be very useful for forensic purposes.

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Year:  1990        PMID: 1977246

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN: 0044-3433


  22 in total

1.  Individual-specific 'fingerprints' of human DNA.

Authors:  A J Jeffreys; V Wilson; S L Thein
Journal:  Nature       Date:  1985 Jul 4-10       Impact factor: 49.962

2.  Application of deoxyribonucleic acid (DNA) polymorphisms to the analysis of DNA recovered from sperm.

Authors:  A Giusti; M Baird; S Pasquale; I Balazs; J Glassberg
Journal:  J Forensic Sci       Date:  1986-04       Impact factor: 1.832

3.  A mapped set of DNA markers for human chromosome 17.

Authors:  Y Nakamura; M Lathrop; P O'Connell; M Leppert; D Barker; E Wright; M Skolnick; S Kondoleon; M Litt; J M Lalouel
Journal:  Genomics       Date:  1988-05       Impact factor: 5.736

4.  Allele frequency distribution of two highly polymorphic DNA sequences in three ethnic groups and its application to the determination of paternity.

Authors:  M Baird; I Balazs; A Giusti; L Miyazaki; L Nicholas; K Wexler; E Kanter; J Glassberg; F Allen; P Rubinstein
Journal:  Am J Hum Genet       Date:  1986-10       Impact factor: 11.025

5.  Hypervariable polymorphic VNTR loci for parentage testing and individual identification.

Authors:  T Yokoi; M Nata; T Odaira; K Sagisaka
Journal:  Jinrui Idengaku Zasshi       Date:  1990-06

6.  Highly variable regions of DNA flank the human alpha globin genes.

Authors:  D R Higgs; S E Goodbourn; J S Wainscoat; J B Clegg; D J Weatherall
Journal:  Nucleic Acids Res       Date:  1981-09-11       Impact factor: 16.971

7.  Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue.

Authors:  D J Capon; E Y Chen; A D Levinson; P H Seeburg; D V Goeddel
Journal:  Nature       Date:  1983-03-03       Impact factor: 49.962

8.  Human population genetic studies of five hypervariable DNA loci.

Authors:  I Balazs; M Baird; M Clyne; E Meade
Journal:  Am J Hum Genet       Date:  1989-02       Impact factor: 11.025

9.  Characteristics of a DNA probe (pa3'HVR) when used for paternity testing.

Authors:  R W Allen; B Bliss; A Pearson
Journal:  Transfusion       Date:  1989 Jul-Aug       Impact factor: 3.157

10.  Forensic application of DNA 'fingerprints'.

Authors:  P Gill; A J Jeffreys; D J Werrett
Journal:  Nature       Date:  1985 Dec 12-18       Impact factor: 49.962

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  1 in total

1.  Application of single-locus hypervariable region DNA probes to deficiency cases in paternity testing.

Authors:  T Yokoi; T Odaira; M Nata; Y Aoki; K Sagisaka
Journal:  Int J Legal Med       Date:  1991-03       Impact factor: 2.686

  1 in total

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