Literature DB >> 19770320

Is breast MRI helpful in the evaluation of inconclusive mammographic findings?

Linda Moy1, Kristin Elias, Vashali Patel, Jiyon Lee, James S Babb, Hildegard K Toth, Cecilia L Mercado.   

Abstract

OBJECTIVE: The purpose of this study was to evaluate the usefulness of MRI of the breast in cases in which mammographic or sonographic findings are inconclusive.
MATERIALS AND METHODS: We retrospectively reviewed images from 115 MRI examinations of the breast performed from 1999 to 2005 for the indication of problem-solving for inconclusive findings on a mammogram. Forty-eight of the 115 women (41.8%) were at high risk. We discerned whether sonography or MRI was used as an adjunctive tool and correlated the findings with those in the pathology database.
RESULTS: The equivocal findings most frequently leading to MRI were asymmetry and architectural distortion. No suspicious MRI correlate was found in 100 of 115 cases (87%). These cases were found stable at follow-up mammography or MRI after a mean of 34 months. Fifteen enhancing masses (13%) that corresponded to the mammographic abnormality were seen on MR images. All masses identified at MRI were accurately localized for biopsy, and six malignant lesions were identified. Four of six malignant tumors were seen in one mammographic view only; two were seen on second-look ultrasound images. MRI had a sensitivity of 100% and compared with mammography had significantly higher specificity (91.7% vs 80.7%, p = 0.029), positive predictive value (40% vs 8.7%, p = 0.032), and overall accuracy (92.2% vs 78.3%, p = 0.0052). Eighteen incidental lesions (15.7%) were detected at MRI, and all were subsequently found benign.
CONCLUSION: We found breast MRI to be a useful adjunctive tool when findings at conventional imaging were equivocal. Strict patient selection criteria should be used because of the high frequency of incidental lesions seen on MR images.

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Mesh:

Year:  2009        PMID: 19770320     DOI: 10.2214/AJR.08.1229

Source DB:  PubMed          Journal:  AJR Am J Roentgenol        ISSN: 0361-803X            Impact factor:   3.959


  20 in total

1.  The added value of quantitative multi-voxel MR spectroscopy in breast magnetic resonance imaging.

Authors:  M D Dorrius; R M Pijnappel; M C van der Weide Jansen; L Jansen; P Kappert; M Oudkerk; P E Sijens
Journal:  Eur Radiol       Date:  2011-11-11       Impact factor: 5.315

2.  Problem-solving breast MRI: useful or a source of new problems?

Authors:  Füsun Taşkın; Yasemin Polat; İbrahim H Erdoğdu; Figen T Türkdoğan; Veli Suha Öztürk; Serdar Özbaş
Journal:  Diagn Interv Radiol       Date:  2018-09       Impact factor: 2.630

3.  Additional diagnostic value of MRI in patients with suspicious breast lesions based on ultrasound.

Authors:  O Sarica; F Uluc
Journal:  Br J Radiol       Date:  2014-07-01       Impact factor: 3.039

4.  Breast cancer: a new imaging approach as an addition to existing guidelines.

Authors:  Monique D Dorrius; Erik F J de Vries; Riemer H J A Slart; Andor W J M Glaudemans
Journal:  Eur J Nucl Med Mol Imaging       Date:  2015-03-12       Impact factor: 9.236

5.  Magnetic resonance imaging texture analysis classification of primary breast cancer.

Authors:  S A Waugh; C A Purdie; L B Jordan; S Vinnicombe; R A Lerski; P Martin; A M Thompson
Journal:  Eur Radiol       Date:  2015-06-12       Impact factor: 5.315

6.  Is there a role for magnetic resonance imaging in diagnosing palpable breast masses when mammogram and ultrasound are negative?

Authors:  Molly L Olsen; Marilyn J Morton; Daniela L Stan; Sandhya Pruthi
Journal:  J Womens Health (Larchmt)       Date:  2012-10-09       Impact factor: 2.681

Review 7.  Ultrasound Imaging Technologies for Breast Cancer Detection and Management: A Review.

Authors:  Rongrong Guo; Guolan Lu; Binjie Qin; Baowei Fei
Journal:  Ultrasound Med Biol       Date:  2017-10-26       Impact factor: 2.998

8.  Indications for breast magnetic resonance imaging at a referral center for the diagnosis and treatment of breast cancer in Brazil.

Authors:  Samuel Silva Ferreira; Adriene Moraes Campos; Patrícia Lima Fernandes; Izabela Machado Pereira; Flavia Maria Rodrigues; Antônio Fernando Braga Ferreira Victor; Ivie Braga de Paula
Journal:  Radiol Bras       Date:  2021 Mar-Apr

Review 9.  Breast magnetic resonance imaging as a problem-solving modality in mammographic BI-RADS 3 lesions.

Authors:  M D Dorrius; R M Pijnappel; M C Jansen-van der Weide; M Oudkerk
Journal:  Cancer Imaging       Date:  2010-10-04       Impact factor: 3.909

10.  Differentiation of breast cancer from fibroadenoma with dual-echo dynamic contrast-enhanced MRI.

Authors:  Shiwei Wang; Zachary Delproposto; Haoyu Wang; Xuewei Ding; Conghua Ji; Bei Wang; Maosheng Xu
Journal:  PLoS One       Date:  2013-07-02       Impact factor: 3.240

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