| Literature DB >> 19768583 |
Sylvain Ladoire1, Caroline Beynat, Pierre Diaz, Bruno Coudert, Laure Favier, François Ghiringhelli.
Abstract
Spontaneous pyopneumothorax is a very rare occurrence, even in cancer treated patients. Here we present two consecutive cases of spontaneous pyopneumothorax that occurred early after initiation of mTOR inhibitors for the treatment of renal cell carcinoma with subpleural pulmonary metastasis. In these two cases, necrosis and excavation of lung metastasis were observed, suggesting their involvement in the pathogenic mechanism of pyopneumothorax. This report extends the available experience of the pulmonary side effects of these novel targeted therapies.Entities:
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Year: 2009 PMID： 19768583 DOI： 10.1007/s12032-009-9311-z
Source DB: PubMed Journal: Med Oncol ISSN： 1357-0560 Impact factor: 3.064