OBJECTIVE: The aim of this study was to carry out an in vivo assessment of bone ingrowth in two different types of porous titanium -the first being completely porous, and the second with a porous surface and dense nucleus, manufactured by powder metallurgy- and to evaluate their mechanical properties. STUDY DESIGN: Ten scaffolds from each group were submitted to metallographic analysis and compression tests. Next, two scaffolds of each type were inserted into 14 rabbits, which were sacrificed 8 weeks after surgery. The samples were submitted for histological examination. RESULTS: Metallographic analysis revealed interconnected pores, and the average interconnected pore diameter was about 360 mm, with 36% total porosity. The totally porous titanium samples and the titanium samples with porous surface and dense nucleus showed an average compressive strength of 16.19 MPa and 69.27 MPa, respectively. After 8 weeks, the animals showed bone ingrowth, even into the most internal pores. CONCLUSIONS: The pore morphology was effective in permitting bone ingrowth in both groups. Titanium scaffolds with a porous surface and dense nucleus showed the best mechanical properties and most adequate interface.
OBJECTIVE: The aim of this study was to carry out an in vivo assessment of bone ingrowth in two different types of porous titanium -the first being completely porous, and the second with a porous surface and dense nucleus, manufactured by powder metallurgy- and to evaluate their mechanical properties. STUDY DESIGN: Ten scaffolds from each group were submitted to metallographic analysis and compression tests. Next, two scaffolds of each type were inserted into 14 rabbits, which were sacrificed 8 weeks after surgery. The samples were submitted for histological examination. RESULTS: Metallographic analysis revealed interconnected pores, and the average interconnected pore diameter was about 360 mm, with 36% total porosity. The totally porous titanium samples and the titanium samples with porous surface and dense nucleus showed an average compressive strength of 16.19 MPa and 69.27 MPa, respectively. After 8 weeks, the animals showed bone ingrowth, even into the most internal pores. CONCLUSIONS: The pore morphology was effective in permitting bone ingrowth in both groups. Titanium scaffolds with a porous surface and dense nucleus showed the best mechanical properties and most adequate interface.
Authors: Luana Marotta Reis de Vasconcellos; Fernanda Nascimento Oliveira; Daniel de Oliveira Leite; Luis Gustavo Oliveira de Vasconcellos; Renata Falchete do Prado; Carolina Judica Ramos; Mário Lima de Alencastro Graça; Carlos Alberto Alves Cairo; Yasmin Rodarte Carvalho Journal: J Mater Sci Mater Med Date: 2011-12-20 Impact factor: 3.896
Authors: Renata Falchete do Prado; Gabriela Campos Esteves; Evelyn Luzia De Souza Santos; Daiane Acácia Griti Bueno; Carlos Alberto Alves Cairo; Luis Gustavo Oliveira De Vasconcellos; Renata Silveira Sagnori; Fernanda Bastos Pereira Tessarin; Felipe Eduardo Oliveira; Luciane Dias De Oliveira; Maria Fernanda Lima Villaça-Carvalho; Vinicius André Rodrigues Henriques; Yasmin Rodarte Carvalho; Luana Marotta Reis De Vasconcellos Journal: PLoS One Date: 2018-05-17 Impact factor: 3.240