Literature DB >> 19766556

Attacking cancer at its root.

Craig B Thompson1.   

Abstract

This year the Lasker DeBakey Clinical Research Award will be shared by Brian Druker, Nicholas Lydon, and Charles Sawyers for their development of a targeted molecular therapy for treating chronic myeloid leukemia. Their work demonstrated the ability of drugs directed against cancer-causing oncogenes to turn a rapidly fatal malignancy into a manageable chronic disease.

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Year:  2009        PMID： 19766556     DOI： 10.1016/j.cell.2009.09.002

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  16 in total

Review 1.  Network-based approaches in drug discovery and early development.

Authors:  J M Harrold; M Ramanathan; D E Mager
Journal:  Clin Pharmacol Ther       Date:  2013-09-11       Impact factor: 6.875

Review 2.  tRNA-derived fragments (tRFs): establishing their turf in post-transcriptional gene regulation.

Authors:  Srikar Krishna; Srikala Raghavan; Ramanuj DasGupta; Dasaradhi Palakodeti
Journal:  Cell Mol Life Sci       Date:  2021-01-02       Impact factor: 9.261

Review 3.  The genetic basis of kidney cancer: a metabolic disease.

Authors:  W Marston Linehan; Ramaprasad Srinivasan; Laura S Schmidt
Journal:  Nat Rev Urol       Date:  2010-05       Impact factor: 14.432

Review 4.  Cytogenomics of cancers: from chromosome to sequence.

Authors:  Alain Bernheim
Journal:  Mol Oncol       Date:  2010-06-11       Impact factor: 6.603

5.  Lactate detection in inducible and orthotopic Her2/neu mammary gland tumours in mouse models.

Authors:  S Magnitsky; G K Belka; C Sterner; S Pickup; L A Chodosh; J D Glickson
Journal:  NMR Biomed       Date:  2012-07-05       Impact factor: 4.044

6.  A magnetic bead-based protein kinase assay with dual detection techniques.

Authors:  Guangchang Zhou; Juliesta E Sylvester; Ding Wu; Darren R Veach; Stephen J Kron
Journal:  Anal Biochem       Date:  2010-08-31       Impact factor: 3.365

7.  Towards patient-based cancer therapeutics.

Authors:  Stuart L Schreiber; Alykhan F Shamji; Paul A Clemons; Cindy Hon; Angela N Koehler; Benito Munoz; Michelle Palmer; Andrew M Stern; Bridget K Wagner; Scott Powers; Scott W Lowe; Xuecui Guo; Alex Krasnitz; Eric T Sawey; Raffaella Sordella; Lincoln Stein; Lloyd C Trotman; Andrea Califano; Riccardo Dalla-Favera; Adolfo Ferrando; Antonio Iavarone; Laura Pasqualucci; José Silva; Brent R Stockwell; William C Hahn; Lynda Chin; Ronald A DePinho; Jesse S Boehm; Shuba Gopal; Alan Huang; David E Root; Barbara A Weir; Daniela S Gerhard; Jean Claude Zenklusen; Michael G Roth; Michael A White; John D Minna; John B MacMillan; Bruce A Posner
Journal:  Nat Biotechnol       Date:  2010-09       Impact factor: 54.908

8.  Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l.

Authors:  L Chen; A J Deshpande; D Banka; K M Bernt; S Dias; C Buske; E J Olhava; S R Daigle; V M Richon; R M Pollock; S A Armstrong
Journal:  Leukemia       Date:  2012-11-09       Impact factor: 11.528

9.  Effect of dietary patterns differing in carbohydrate and fat content on blood lipid and glucose profiles based on weight-loss success of breast-cancer survivors.

Authors:  Henry J Thompson; Scot M Sedlacek; Devchand Paul; Pamela Wolfe; John N McGinley; Mary C Playdon; Elizabeth A Daeninck; Sara N Bartels; Mark R Wisthoff
Journal:  Breast Cancer Res       Date:  2012-01-06       Impact factor: 6.466

10.  Drug-tolerant cancer cells show reduced tumor-initiating capacity: depletion of CD44 cells and evidence for epigenetic mechanisms.

Authors:  Hong Yan; Xin Chen; Qiuping Zhang; Jichao Qin; Hangwen Li; Can Liu; Tammy Calhoun-Davis; Luis Della Coletta; Jim Klostergaard; Izabela Fokt; Stanislaw Skora; Waldemar Priebe; Yongyi Bi; Dean G Tang
Journal:  PLoS One       Date:  2011-09-15       Impact factor: 3.240
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