Literature DB >> 19765711

Fluid-structure interaction analysis of turbulent pulsatile flow within a layered aortic wall as related to aortic dissection.

Khalil Khanafer1, Ramon Berguer.   

Abstract

Turbulent pulsatile flow and wall mechanics were studied numerically in an axisymmetric three-layered wall model of a descending aorta. The transport equations were solved using the finite element formulation based on the Galerkin method of weighted residuals. A fully-coupled fluid-structure interaction (FSI) analysis was utilized in this investigation. We calculated Von Mises wall stress, streamlines and fluid pressure contours. The findings of this study show that peak wall stress and maximum shear stress are highest in the media layer. The difference in the elastic properties of contiguous layers of the wall of the aorta probably determines the occurrence of dissection in the media layer. Moreover, the presence of aortic intramural hematoma is found to have a significant effect on the peak wall stress acting on the inner layer.

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Year:  2009        PMID: 19765711     DOI: 10.1016/j.jbiomech.2009.08.010

Source DB:  PubMed          Journal:  J Biomech        ISSN: 0021-9290            Impact factor:   2.712


  16 in total

1.  Multilayer flow modulator enhances vital organ perfusion in patients with type B aortic dissection.

Authors:  Farhad Rikhtegar Nezami; Lambros S Athanasiou; Junedh M Amrute; Elazer R Edelman
Journal:  Am J Physiol Heart Circ Physiol       Date:  2018-08-10       Impact factor: 4.733

2.  Investigation of material modeling in fluid-structure interaction analysis of an idealized three-layered abdominal aorta: aneurysm initiation and fully developed aneurysms.

Authors:  Fatma Gulden Simsek; Young W Kwon
Journal:  J Biol Phys       Date:  2015-01-27       Impact factor: 1.365

3.  Multi-component model of intramural hematoma.

Authors:  Martina Bukač; Mark Alber
Journal:  J Biomech       Date:  2016-11-15       Impact factor: 2.712

4.  Increased ascending aortic wall stress in patients with bicuspid aortic valves.

Authors:  Derek P Nathan; Chun Xu; Ted Plappert; Benoit Desjardins; Joseph H Gorman; Joseph E Bavaria; Robert C Gorman; Krishnan B Chandran; Benjamin M Jackson
Journal:  Ann Thorac Surg       Date:  2011-08-25       Impact factor: 4.330

Review 5.  Possible mechanical roles of glycosaminoglycans in thoracic aortic dissection and associations with dysregulated transforming growth factor-β.

Authors:  J D Humphrey
Journal:  J Vasc Res       Date:  2012-09-25       Impact factor: 1.934

6.  Biomechanical roles of medial pooling of glycosaminoglycans in thoracic aortic dissection.

Authors:  Sara Roccabianca; Gerard A Ateshian; Jay D Humphrey
Journal:  Biomech Model Mechanobiol       Date:  2013-03-15

7.  Oxidative stress modulates vascular smooth muscle cell phenotype via CTGF in thoracic aortic aneurysm.

Authors:  Emanuela Branchetti; Paolo Poggio; Rachana Sainger; Eric Shang; Juan B Grau; Benjamin M Jackson; Eric K Lai; Michael S Parmacek; Robert C Gorman; Joseph H Gorman; Joseph E Bavaria; Giovanni Ferrari
Journal:  Cardiovasc Res       Date:  2013-08-28       Impact factor: 10.787

8.  Design and in vitro assessment of an improved, low-resistance compliant thoracic artificial lung.

Authors:  Rebecca E Schewe; Khalil M Khanafer; Aarthi Arab; Jeffrey A Mitchell; David J Skoog; Keith E Cook
Journal:  ASAIO J       Date:  2012 Nov-Dec       Impact factor: 2.872

9.  Difference in hemodynamic and wall stress of ascending thoracic aortic aneurysms with bicuspid and tricuspid aortic valve.

Authors:  Salvatore Pasta; Antonino Rinaudo; Angelo Luca; Michele Pilato; Cesare Scardulla; Thomas G Gleason; David A Vorp
Journal:  J Biomech       Date:  2013-05-08       Impact factor: 2.712

10.  Aortic dissection simulation models for clinical support: fluid-structure interaction vs. rigid wall models.

Authors:  Mona Alimohammadi; Joseph M Sherwood; Morad Karimpour; Obiekezie Agu; Stavroula Balabani; Vanessa Díaz-Zuccarini
Journal:  Biomed Eng Online       Date:  2015-04-15       Impact factor: 2.819

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