| Literature DB >> 19752275 |
Wen-han Zhu1, Lan Luo, Jia-yi Wang, Xiao-hong Zhuang, Ling Zhong, Kang Liao, Yan Zeng, Yong-jun Lu.
Abstract
In this work we report the characterization of plasmid pCTX-M360, isolated from a Klebsiella pneumoniae strain from China and encoding the CTX-M-3 extended-spectrum beta-lactamase. Sequence analysis of pCTX-M360 revealed extensive similarity with pEL60 and pCTX-M3, two other enterobacterial plasmids of the IncL/M incompatibility group. Compared to pEL60, pCTX-M360 contains several insertions but lacks most of a 27-kb insert found in pCTX-M3, suggesting that it could be an evolutionary intermediate between pEL60 and pCTX-M3.Entities:
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Year: 2009 PMID: 19752275 PMCID: PMC2786365 DOI: 10.1128/AAC.00032-09
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191