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Literature DB >> 1974879

Genetic mapping in the region of the mouse X-inactivation center.

J T Keer¹, R M Hamvas, N Brockdorff, D Page, S Rastan, S D Brown.

Abstract

The mouse X-inactivation center lies just distal to the T16H breakpoint. Utilizing pedigree analysis of backcross progeny from a Mus domesticus/Mus spretus interspecific cross, we have mapped a number of genetic loci, gene probes, microclones, and EagI linking clones distal to the T16H breakpoint. The genetic analysis provides a detailed genetic map in the vicinity of the mouse X-inactivation center. Comparative mapping data from the human X chromosome indicate that the most probable location of the mouse X-inactivation center is distal to Ccg-1 and in the region of the Pgk-1 locus. We report the assignment of two new loci, EM13 and DXSmh44, to the Ccg-1/Pgk-1 interval.

Entities: Gene Mutation Species

Mesh：

Year: 1990 PMID： 1974879 DOI： 10.1016/0888-7543(90)90200-e

Source DB: PubMed Journal: Genomics ISSN： 0888-7543 Impact factor: 5.736

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Cited

9 in total

Review 1. Mouse X chromosome.

Authors: S D Brown; P Avner; G E Herman
Journal: Mamm Genome Date: 1992 Impact factor: 2.957

2. Localization of the translocation breakpoint in a female with Menkes syndrome to Xq13.2-q13.3 proximal to PGK-1.

Authors: V Verga; B K Hall; S R Wang; S Johnson; J V Higgins; T W Glover
Journal: Am J Hum Genet Date: 1991-06 Impact factor: 11.025

Review 3. Mouse X chromosome.

Authors: S D Brown; P Avner; V M Chapman; R M Hamvas; G E Herman
Journal: Mamm Genome Date: 1991 Impact factor: 2.957

4. Methylation status of CpG sites and methyl-CpG binding proteins are involved in the promoter regulation of the mouse Xist gene.

Authors: N Allaman-Pillet; A Djemaï; C Bonny; D F Schorderet
Journal: Gene Expr Date: 1998

9. Parental imprinting studied by allele-specific primer extension after PCR: paternal X chromosome-linked genes are transcribed prior to preferential paternal X chromosome inactivation.

Authors: J Singer-Sam; V Chapman; J M LeBon; A D Riggs
Journal: Proc Natl Acad Sci U S A Date: 1992-11-01 Impact factor: 11.205

9 in total

Genetic mapping in the region of the mouse X-inactivation center.

Review 1. Mouse X chromosome.

2. Localization of the translocation breakpoint in a female with Menkes syndrome to Xq13.2-q13.3 proximal to PGK-1.

Review 3. Mouse X chromosome.

4. Methylation status of CpG sites and methyl-CpG binding proteins are involved in the promoter regulation of the mouse Xist gene.

5. The 5' repeat elements of the mouse Xist gene inhibit the transcription of X-linked genes.

6. Mapping of a mouse homolog of a heterochromatin protein gene the X chromosome.

Review 7. Long nonoding RNAs in the X-inactivation center.

8. Molecular genetic analysis of the Ta25H deletion: evidence for additional deleted loci.

9. Parental imprinting studied by allele-specific primer extension after PCR: paternal X chromosome-linked genes are transcribed prior to preferential paternal X chromosome inactivation.