| Literature DB >> 19740656 |
Hongzhi Cao1, Saddam Muthana, Yanhong Li, Jiansong Cheng, Xi Chen.
Abstract
A convenient chemoenzymatic strategy for synthesizing sialosides containing a C5-diversified sialic acid was developed. The alpha2,3- and alpha2,6-linked sialosides containing a 5-azido neuraminic acid synthesized by a highly efficient one-pot three-enzyme approach were converted to C5''-amino sialosides, which were used as common intermediates for chemical parallel synthesis to quickly generate a series of sialosides containing various sialic acid forms.Entities:
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Year: 2009 PMID： 19740656 PMCID： PMC2753693 DOI： 10.1016/j.bmcl.2009.08.078
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823