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Literature DB >> 19734920

Nanomedicine: Silence the target.

Abstract

A new formulation of magnetic nanoparticles steered to cells by external magnets can deliver nucleic acids to turn off the growth of tumour blood vessels in mice.

Entities: Disease Species

Mesh：

Substances：
Drug Carriers
DNA

Year: 2009 PMID： 19734920 DOI： 10.1038/nnano.2009.251

Source DB: PubMed Journal: Nat Nanotechnol ISSN： 1748-3387 Impact factor: 39.213

11 in total

1. Generation of magnetic nonviral gene transfer agents and magnetofection in vitro.

Authors: Olga Mykhaylyk; Yolanda Sánchez Antequera; Dialekti Vlaskou; Christian Plank
Journal: Nat Protoc Date: 2007 Impact factor: 13.491

2. Magnetic microspheres: a model system of site specific drug delivery in vivo.

Authors: K J Widder; A E Senyel; G D Scarpelli
Journal: Proc Soc Exp Biol Med Date: 1978-06

3. Magnetically controlled focal intravascular thrombosis in dogs.

Authors: J F Alksne; A G Fingerhut; R W Rand
Journal: J Neurosurg Date: 1966-11 Impact factor: 5.115

4. A novel magnetic crystal-lipid nanostructure for magnetically guided in vivo gene delivery.

Authors: Yoshihisa Namiki; Tamami Namiki; Hiroshi Yoshida; Yukiko Ishii; Akihito Tsubota; Shigeo Koido; Kouichi Nariai; Makoto Mitsunaga; Satoru Yanagisawa; Hideyuki Kashiwagi; Yasuo Mabashi; Yoko Yumoto; Sadayori Hoshina; Kiyotaka Fujise; Norio Tada
Journal: Nat Nanotechnol Date: 2009-08-23 Impact factor: 39.213

5. Clinical experiences with magnetic drug targeting: a phase I study with 4'-epidoxorubicin in 14 patients with advanced solid tumors.

Authors: A S Lübbe; C Bergemann; H Riess; F Schriever; P Reichardt; K Possinger; M Matthias; B Dörken; F Herrmann; R Gürtler; P Hohenberger; N Haas; R Sohr; B Sander; A J Lemke; D Ohlendorf; W Huhnt; D Huhn
Journal: Cancer Res Date: 1996-10-15 Impact factor: 12.701

Review 6. siRNA delivery systems for cancer treatment.

Authors: Yu-Kyoung Oh; Tae Gwan Park
Journal: Adv Drug Deliv Rev Date: 2009-05-05 Impact factor: 15.470

Review 7. Lipid-based systemic delivery of siRNA.

Authors: Yu-Cheng Tseng; Subho Mozumdar; Leaf Huang
Journal: Adv Drug Deliv Rev Date: 2009-03-26 Impact factor: 15.470

8. Tumor regression by targeted gene delivery to the neovasculature.

Authors: John D Hood; Mark Bednarski; Ricardo Frausto; Samira Guccione; Ralph A Reisfeld; Rong Xiang; David A Cheresh
Journal: Science Date: 2002-06-28 Impact factor: 47.728

9. MRI after magnetic drug targeting in patients with advanced solid malignant tumors.

Authors: A-J Lemke; M-I Senfft von Pilsach; A Lübbe; C Bergemann; H Riess; R Felix
Journal: Eur Radiol Date: 2004-08-05 Impact factor: 5.315

10. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.

Authors: Kenneth P Olive; Michael A Jacobetz; Christian J Davidson; Aarthi Gopinathan; Dominick McIntyre; Davina Honess; Basetti Madhu; Mae A Goldgraben; Meredith E Caldwell; David Allard; Kristopher K Frese; Gina Denicola; Christine Feig; Chelsea Combs; Stephen P Winter; Heather Ireland-Zecchini; Stefanie Reichelt; William J Howat; Alex Chang; Mousumi Dhara; Lifu Wang; Felix Rückert; Robert Grützmann; Christian Pilarsky; Kamel Izeradjene; Sunil R Hingorani; Pearl Huang; Susan E Davies; William Plunkett; Merrill Egorin; Ralph H Hruban; Nigel Whitebread; Karen McGovern; Julian Adams; Christine Iacobuzio-Donahue; John Griffiths; David A Tuveson
Journal: Science Date: 2009-05-21 Impact factor: 47.728

5 in total

Nanomedicine: Silence the target.

1. Generation of magnetic nonviral gene transfer agents and magnetofection in vitro.

2. Magnetic microspheres: a model system of site specific drug delivery in vivo.

3. Magnetically controlled focal intravascular thrombosis in dogs.

4. A novel magnetic crystal-lipid nanostructure for magnetically guided in vivo gene delivery.

5. Clinical experiences with magnetic drug targeting: a phase I study with 4'-epidoxorubicin in 14 patients with advanced solid tumors.

Review 6. siRNA delivery systems for cancer treatment.

Review 7. Lipid-based systemic delivery of siRNA.

8. Tumor regression by targeted gene delivery to the neovasculature.

9. MRI after magnetic drug targeting in patients with advanced solid malignant tumors.

10. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.

Review 1. The potential of magneto-electric nanocarriers for drug delivery.

Review 2. In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles.

3. Nuclear mapping of nanodrug delivery systems in dynamic cellular environments.

Review 4. Nanotheranostics: A Possible Solution for Drug-Resistant Staphylococcus aureus and their Biofilms?

Review 5. Perspective of Fe3O4 Nanoparticles Role in Biomedical Applications.