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Literature DB >> 197300

Inhibition by somatostatin of adenosine-3',5'-monophosphate stimulated hepatic ribosomal protein synthesis.

Abstract

Somatostatin which inhibits the secretion of various pituitary and intestinal hormones has been suspected to exert these effects by inhibiting adenosine-3',5'-monophosphate accumulation in the respective endocrine gland. Our results, obtained by cell free protein synthesis and by sedimentation through sucrose gradients of ribosomes, prepared from rat liver after incubation with cyclic AMP and/or somatostatin also suggest this antagonism between somatostatin and cyclic AMP. In addition, they indicate that this antagonism is not restricted to endocrine tissues.

Entities: Chemical Gene Species

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Year: 1977 PMID： 197300 DOI： 10.1007/bf01478838

Source DB: PubMed Journal: Klin Wochenschr ISSN： 0023-2173

14 in total

Review 1. Somatostatin.

Authors: W Vale; P Brazeau; C Rivier; M Brown; B Boss; J Rivier; R Burgus; N Ling; R Guillemin
Journal: Recent Prog Horm Res Date: 1975

2. Somatostatin: hypothalamic inhibitor of the endocrine pancreas.

Authors: D J Koerker; W Ruch; E Chideckel; J Palmer; C J Goodner; J Ensinck; C C Gale
Journal: Science Date: 1974-04-26 Impact factor: 47.728

3. Inhibition of adenosine 3',5'-monophosphate accumulation in anterior pituitary gland in vitro by growth hormone-release inhibiting hormone.

Authors: P Borgeat; F Labrie; J Drouin; A Bélanger; H Immer; K Sestanj; V Nelson; M Götz; A V Schally; D H Coy; E J Coy
Journal: Biochem Biophys Res Commun Date: 1974-02-27 Impact factor: 3.575

4. Hormone-dependent phosphorylation of ribosomal and plasma membrane proteins in mouse mammary gland in vitro.

Authors: G C Majumder; R W Turkington
Journal: J Biol Chem Date: 1972-11-25 Impact factor: 5.157

5. Adenosine 3',5'-monophosphate-dependent protein kinase from bovine anterior pituitary gland. I. Properties.

Authors: F Labrie; S Lemaire; C Courte
Journal: J Biol Chem Date: 1971-12-10 Impact factor: 5.157

6. Actinomycin-insensitive stimulation of protein synthesis in rat anterior pituitary in vitro by dibutyryl adenosine 3',5'-monophosphate.

Authors: F Labrie; G Béraud; M Gauthier; A Lemay
Journal: J Biol Chem Date: 1971-03-25 Impact factor: 5.157

7. Stimulation by adenosine 3',5'-cyclic monophosphate of protein synthesis by adenohypophyseal polyribosomes.

Authors: P R Adiga; P V Murthy; J M McKenzie
Journal: Biochemistry Date: 1971-02-16 Impact factor: 3.162

8. Further studies of stimulation of anterior pituitary cyclic adenosine 3',5'-monophosphate formation by hypothalamic extract and prostaglandins.

Authors: U Zor; T Kaneko; H P Schneider; S M McCann; J B Field
Journal: J Biol Chem Date: 1970-06-10 Impact factor: 5.157

9. Stimulatory and inhibitory effects of purified hypothalamic extracts on growth hormone release from rat pituitary in vitro.

Authors: L Krulich; A P Dhariwal; S M McCann
Journal: Endocrinology Date: 1968-10 Impact factor: 4.736