Literature DB >> 19728795

Fyn kinase function in lipid utilization: a new upstream regulator of AMPK activity?

Manu Vatish1, Eijiro Yamada, Jeffrey E Pessin, Claire C Bastie.   

Abstract

The balance of cellular energy levels in response to changes of nutrient availability, stress stimuli or exercise is a critical step in maintaining tissue and whole body homeostasis. Disruption of this balance is associated with various pathologies, including the metabolic syndrome. Recently, accumulating evidence has demonstrated that the AMP-activated protein kinase (AMPK) plays a central role in sensing changes in energy levels. The regulation of AMPK activity is currently the subject of significant investigation since this enzyme is a potential therapeutic target in both metabolic disorders and tumorigenesis. In this review, we present novel evidence of crosstalk between Fyn, one member of the Src kinase family, and AMPK.

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Year:  2009        PMID： 19728795      PMCID： PMC4324608          DOI： 10.1080/13813450903164348

Source DB:  PubMed          Journal:  Arch Physiol Biochem        ISSN： 1381-3455            Impact factor:   4.076


  82 in total

Review 1.  Structure and regulation of Src family kinases.

Authors:  Titus J Boggon; Michael J Eck
Journal:  Oncogene       Date:  2004-10-18       Impact factor: 9.867

2.  Identification of an alternatively spliced isoform of the fyn tyrosine kinase.

Authors:  Jeffrey F Goldsmith; Craig G Hall; T Prescott Atkinson
Journal:  Biochem Biophys Res Commun       Date:  2002-11-08       Impact factor: 3.575

Review 3.  The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction.

Authors:  A C Chan; D M Desai; A Weiss
Journal:  Annu Rev Immunol       Date:  1994       Impact factor: 28.527

4.  Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase.

Authors:  G J Della Rocca; T van Biesen; Y Daaka; D K Luttrell; L M Luttrell; R J Lefkowitz
Journal:  J Biol Chem       Date:  1997-08-01       Impact factor: 5.157

5.  A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway.

Authors:  Min Xie; Dou Zhang; Jason R B Dyck; Yi Li; Hui Zhang; Masae Morishima; Douglas L Mann; George E Taffet; Antonio Baldini; Dirar S Khoury; Michael D Schneider
Journal:  Proc Natl Acad Sci U S A       Date:  2006-11-03       Impact factor: 11.205

6.  Effect of fasting on PPARgamma and AMPK activity in adipocytes.

Authors:  Kazuo Kajita; Tomoatsu Mune; Takahide Ikeda; Masami Matsumoto; Yoshihiro Uno; Chiyo Sugiyama; Kenji Matsubara; Hiroyuki Morita; Masao Takemura; Mitsuru Seishima; Jun Takeda; Tatsuo Ishizuka
Journal:  Diabetes Res Clin Pract       Date:  2008-06-17       Impact factor: 5.602

7.  Insulin resistance in skeletal muscles of caveolin-3-null mice.

Authors:  Jin Oshikawa; Koji Otsu; Yoshiyuki Toya; Takashi Tsunematsu; Raleigh Hankins; Jun-ichi Kawabe; Susumu Minamisawa; Satoshi Umemura; Yasuko Hagiwara; Yoshihiro Ishikawa
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-16       Impact factor: 11.205

8.  Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome.

Authors:  Toshiya Tanaka; Joji Yamamoto; Satoshi Iwasaki; Hiroshi Asaba; Hiroki Hamura; Yukio Ikeda; Mitsuhiro Watanabe; Kenta Magoori; Ryoichi X Ioka; Keisuke Tachibana; Yuichiro Watanabe; Yasutoshi Uchiyama; Koichi Sumi; Haruhisa Iguchi; Sadayoshi Ito; Takefumi Doi; Takao Hamakubo; Makoto Naito; Johan Auwerx; Masashi Yanagisawa; Tatsuhiko Kodama; Juro Sakai
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-15       Impact factor: 11.205

9.  AMPK beta subunit targets metabolic stress sensing to glycogen.

Authors:  Galina Polekhina; Abhilasha Gupta; Belinda J Michell; Bryce van Denderen; Sid Murthy; Susanne C Feil; Ian G Jennings; Duncan J Campbell; Lee A Witters; Michael W Parker; Bruce E Kemp; David Stapleton
Journal:  Curr Biol       Date:  2003-05-13       Impact factor: 10.834

10.  Functional and physical interaction of protein-tyrosine kinases Fyn and Csk in the T-cell signaling system.

Authors:  M Takeuchi; S Kuramochi; N Fusaki; S Nada; J Kawamura-Tsuzuku; S Matsuda; K Semba; K Toyoshima; M Okada; T Yamamoto
Journal:  J Biol Chem       Date:  1993-12-25       Impact factor: 5.157
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  4 in total

1.  Isolation of monobodies that bind specifically to the SH3 domain of the Fyn tyrosine protein kinase.

Authors:  Renhua Huang; Pete Fang; Brian K Kay
Journal:  N Biotechnol       Date:  2011-12-06       Impact factor: 5.079

Review 2.  Current Insights Into Oligodendrocyte Metabolism and Its Power to Sculpt the Myelin Landscape.

Authors:  Mohanlall Narine; Holly Colognato
Journal:  Front Cell Neurosci       Date:  2022-04-28       Impact factor: 6.147

3.  The application of transcriptomic data in the authentication of beef derived from contrasting production systems.

Authors:  Torres Sweeney; Alex Lejeune; Aidan P Moloney; Frank J Monahan; Paul Mc Gettigan; Gerard Downey; Stephen D E Park; Marion T Ryan
Journal:  BMC Genomics       Date:  2016-09-21       Impact factor: 3.969

4.  Strategies towards Improved Feed Efficiency in Pigs Comprise Molecular Shifts in Hepatic Lipid and Carbohydrate Metabolism.

Authors:  Henry Reyer; Michael Oster; Elizabeth Magowan; Dirk Dannenberger; Siriluck Ponsuksili; Klaus Wimmers
Journal:  Int J Mol Sci       Date:  2017-08-01       Impact factor: 5.923
  4 in total

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