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Literature DB >> 19727304

Beyond reliability: biomarkers and validity in psychiatry.

Abstract

The validity of psychiatric diagnosis rests in part on a demonstration that identifiable biomarkers exist for major psychiatric illnesses. Recent evidence supports the existence of several biomarkers or endophenotypes for both schizophrenia and bipolar disorder. As we learn more about how these biomarkers relate to the symptoms, course, and treatment response of major psychiatric disorders, the "objectivity" of psychiatric diagnosis will increase. However, psychiatry is and will remain a clinically based discipline, aimed at comprehensively understanding and relieving human suffering.

Entities: Disease Species

Keywords: objectivity; psychiatric diagnosis; validity

Year: 2008 PMID： 19727304 PMCID： PMC2719547

Source DB: PubMed Journal: Psychiatry (Edgmont) ISSN： 1550-5952

17 in total

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Journal: Mol Psychiatry Date: 2005-01 Impact factor: 15.992

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Authors: Ronald Pies
Journal: Psychiatry (Edgmont) Date: 2007-10

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10. Further evidence of the reliability and validity of DSM-IV ODD and CD in preschool children.

Authors: Kate Keenan; Lauren S Wakschlag; Barbara Danis; Carri Hill; Marisha Humphries; Jeanne Duax; Radiah Donald
Journal: J Am Acad Child Adolesc Psychiatry Date: 2007-04 Impact factor: 8.829

5 in total

1. Multifactoriality in Psychiatric Disorders: A Computational Study of Schizophrenia.

Authors: Rodrigo Pavão; Adriano B L Tort; Olavo B Amaral
Journal: Schizophr Bull Date: 2014-10-20 Impact factor: 9.306

Review 2. Biomarkers in the diagnosis of ADHD--promising directions.

Authors: Stephen V Faraone; Cristian Bonvicini; Catia Scassellati
Journal: Curr Psychiatry Rep Date: 2014-11 Impact factor: 5.285

3. Should DSM-V Designate "Internet Addiction" a Mental Disorder?

Authors: Ronald Pies
Journal: Psychiatry (Edgmont) Date: 2009-02

4. Psychiatric Diagnosis and the Pathologist's View of Schizophrenia.

Authors: Ronald Pies
Journal: Psychiatry (Edgmont) Date: 2008-07

Review 5. Mass spectrometry for the detection of potential psychiatric biomarkers.

Authors: Armand G Ngounou Wetie; Izabela Sokolowska; Kelly Wormwood; Katherine Beglinger; Tanja Maria Michel; Johannes Thome; Costel C Darie; Alisa G Woods
Journal: J Mol Psychiatry Date: 2013-06-05

5 in total