Literature DB >> 19726764

Following the hedgehog to new cancer therapies.

Andrzej A Dlugosz, Moshe Talpaz.   

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Year:  2009        PMID: 19726764     DOI: 10.1056/NEJMe0906092

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


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  15 in total

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3.  Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth.

Authors:  James Kim; Jean Y Tang; Ruoyu Gong; Jynho Kim; John J Lee; Karl V Clemons; Curtis R Chong; Kris S Chang; Mark Fereshteh; Dale Gardner; Tannishtha Reya; Jun O Liu; Ervin H Epstein; David A Stevens; Philip A Beachy
Journal:  Cancer Cell       Date:  2010-04-13       Impact factor: 31.743

4.  Structure of Sonic Hedgehog protein in complex with zinc(II) and magnesium(II) reveals ion-coordination plasticity relevant to peptide drug design.

Authors:  Rachel Bonn-Breach; Yu Gu; Jermaine Jenkins; Rudi Fasan; Joseph Wedekind
Journal:  Acta Crystallogr D Struct Biol       Date:  2019-10-30       Impact factor: 7.652

Review 5.  Novel therapeutic agents against cancer stem cells of chronic myeloid leukemia.

Authors:  Yaoyu Chen; Cong Peng; Con Sullivan; Dongguang Li; Shaoguang Li
Journal:  Anticancer Agents Med Chem       Date:  2010-02       Impact factor: 2.505

6.  The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature.

Authors:  Luowei Li; Suneet Shukla; Andrew Lee; Susan H Garfield; David J Maloney; Suresh V Ambudkar; Stuart H Yuspa
Journal:  Cancer Res       Date:  2010-05-11       Impact factor: 12.701

Review 7.  SHH desmoplastic/nodular medulloblastoma and Gorlin syndrome in the setting of Down syndrome: case report, molecular profiling, and review of the literature.

Authors:  Ross Mangum; Elizabeth Varga; Daniel R Boué; David Capper; Martin Benesch; Jeffrey Leonard; Diana S Osorio; Christopher R Pierson; Nicholas Zumberge; Felix Sahm; Daniel Schrimpf; Stefan M Pfister; Jonathan L Finlay
Journal:  Childs Nerv Syst       Date:  2016-07-21       Impact factor: 1.475

8.  Targeting the SMO oncogene by miR-326 inhibits glioma biological behaviors and stemness.

Authors:  Wenzhong Du; Xing Liu; Lingchao Chen; Zhijin Dou; Xuhui Lei; Liang Chang; Jinquan Cai; Yuqiong Cui; Dongbo Yang; Ying Sun; Yongli Li; Chuanlu Jiang
Journal:  Neuro Oncol       Date:  2014-08-30       Impact factor: 12.300

Review 9.  Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy.

Authors:  James P Sullivan; John D Minna; Jerry W Shay
Journal:  Cancer Metastasis Rev       Date:  2010-03       Impact factor: 9.264

10.  Expression of Bmi1, FoxF1, Nanog, and γ-catenin in relation to hedgehog signaling pathway in human non-small-cell lung cancer.

Authors:  Ioannis P Gialmanidis; Vasiliki Bravou; Ilias Petrou; Helen Kourea; Alexandros Mathioudakis; Ioannis Lilis; Helen Papadaki
Journal:  Lung       Date:  2013-07-18       Impact factor: 2.584

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