| Literature DB >> 19724491 |
Claudio Vinegoni1, Daniel Razansky, Scott A Hilderbrand, Fangwei Shao, Vasilis Ntziachristos, Ralph Weissleder.
Abstract
We report on a systematic study of upconverting fluorescence signal generation within turbid phantoms and real tissues. An accurate three-point Green's function, describing the forward model of photon propagation, is established and experimentally validated. We further demonstrate, for the first time to our knowledge, autofluorescence-free transillumination imaging of mice that have received biocompatible upconverting nanoparticles. The method holds great promise for artifact-free whole-body visualization of optical molecular probes.Entities:
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Year: 2009 PMID: 19724491 PMCID: PMC2749971 DOI: 10.1364/OL.34.002566
Source DB: PubMed Journal: Opt Lett ISSN: 0146-9592 Impact factor: 3.776