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Literature DB >> 19721463

The case for open-access chemical biology. A strategy for pre-competitive medicinal chemistry to promote drug discovery.

Johan Weigelt¹.

Abstract

Mesh：

Year: 2009 PMID： 19721463 PMCID： PMC2750055 DOI： 10.1038/embor.2009.193

Source DB: PubMed Journal: EMBO Rep ISSN： 1469-221X Impact factor: 8.807

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24 in total

Review 1. How many genomics targets can a portfolio afford?

Authors: Ulrich A K Betz
Journal: Drug Discov Today Date: 2005-08-01 Impact factor: 7.851

2. Crystal structure of the CorA Mg2+ transporter.

Authors: Vladimir V Lunin; Elena Dobrovetsky; Galina Khutoreskaya; Rongguang Zhang; Andrzej Joachimiak; Declan A Doyle; Alexey Bochkarev; Michael E Maguire; Aled M Edwards; Christopher M Koth
Journal: Nature Date: 2006-04-06 Impact factor: 49.962

3. Fundamental problems lie ahead in the drug discovery and commercialization process: restructuring of the pharmaceutical industry and an improved partnership with academia are required.

Authors: George J Brewer
Journal: J Investig Med Date: 2006-09 Impact factor: 2.895

4. Drug discovery in jeopardy.

Authors: Pedro Cuatrecasas
Journal: J Clin Invest Date: 2006-11 Impact factor: 14.808

5. Decitabine.

Authors: Steven D Gore; Carole Jones; Peter Kirkpatrick
Journal: Nat Rev Drug Discov Date: 2006-11 Impact factor: 84.694

Review 6. Governmental influences on drug development: striking a better balance.

Authors: Henry I Miller; David R Henderson
Journal: Nat Rev Drug Discov Date: 2007-07 Impact factor: 84.694

Review 7. MMPs as therapeutic targets--still a viable option?

Authors: Barbara Fingleton
Journal: Semin Cell Dev Biol Date: 2007-07-06 Impact factor: 7.727

8. FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma.

Authors: Bhupinder S Mann; John R Johnson; Martin H Cohen; Robert Justice; Richard Pazdur
Journal: Oncologist Date: 2007-10

9. Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.

Authors: Stanley S Ng; Kathryn L Kavanagh; Michael A McDonough; Danica Butler; Ewa S Pilka; Benoit M R Lienard; James E Bray; Pavel Savitsky; Opher Gileadi; Frank von Delft; Nathan R Rose; John Offer; Johanna C Scheinost; Tomasz Borowski; Michael Sundstrom; Christopher J Schofield; Udo Oppermann
Journal: Nature Date: 2007-06-24 Impact factor: 49.962

Review 10. The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.

Authors: Opher Gileadi; Stefan Knapp; Wen Hwa Lee; Brian D Marsden; Susanne Müller; Frank H Niesen; Kathryn L Kavanagh; Linda J Ball; Frank von Delft; Declan A Doyle; Udo C T Oppermann; Michael Sundström
Journal: J Struct Funct Genomics Date: 2007-10-12

8 in total

1. Counterpoint: Do not opine before it's time.

Authors: Isaac S Kohane; David M Margulies
Journal: Nat Biotechnol Date: 2011-03 Impact factor: 54.908

2. Point: Are we prepared for the future doctor visit?

Authors: Stephen H Friend; Trey Ideker
Journal: Nat Biotechnol Date: 2011-03 Impact factor: 54.908

3. A public-private partnership to unlock the untargeted kinome.

Authors: Stefan Knapp; Paulo Arruda; Julian Blagg; Stephen Burley; David H Drewry; Aled Edwards; Doriano Fabbro; Paul Gillespie; Nathanael S Gray; Bernhard Kuster; Karen E Lackey; Paulo Mazzafera; Nicholas C O Tomkinson; Timothy M Willson; Paul Workman; William J Zuercher
Journal: Nat Chem Biol Date: 2013-01 Impact factor: 15.040