Literature DB >> 19720553

LINGO1 rs9652490 is associated with essential tremor and Parkinson disease.

Carles Vilariño-Güell1, Owen A Ross, Christian Wider, Barbara Jasinska-Myga, Stephanie A Cobb, Alexandra I Soto-Ortolaza, Jennifer M Kachergus, Brett H Keeling, Justus C Dachsel, Heather L Melrose, Bahareh Behrouz, Zbigniew K Wszolek, Ryan J Uitti, Jan O Aasly, Alex Rajput, Matthew J Farrer.   

Abstract

Recently, a variant in LINGO1 (rs9652490) was found to associate with increased risk of essential tremor. We set out to replicate this association in an independent case-control series of essential tremor from North America. In addition, given the clinical and pathological overlap between essential tremor and Parkinson disease, we also evaluate the effect of LINGO1 rs9652490 in two case-control series of Parkinson disease. Our study demonstrates a significant association between LINGO1 rs9652490 and essential tremor (P = 0.014) and Parkinson disease (P = 0.0003), thus providing the first evidence of a genetic link between both diseases. Copyright 2009 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19720553      PMCID： PMC2844122          DOI： 10.1016/j.parkreldis.2009.08.006

Source DB:  PubMed          Journal:  Parkinsonism Relat Disord        ISSN： 1353-8020            Impact factor:   4.891


  20 in total

1.  LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex.

Authors:  Sha Mi; Xinhua Lee; Zhaohui Shao; Greg Thill; Benxiu Ji; Jane Relton; Melissa Levesque; Norm Allaire; Steve Perrin; Bryan Sands; Thomas Crowell; Richard L Cate; John M McCoy; R Blake Pepinsky
Journal:  Nat Neurosci       Date:  2004-02-15       Impact factor: 24.884

2.  Diagnostic criteria for essential tremor: a population perspective.

Authors:  E D Louis; B Ford; H Lee; H Andrews; G Cameron
Journal:  Arch Neurol       Date:  1998-06

3.  Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease.

Authors:  A J Hughes; S E Daniel; A J Lees
Journal:  Neurology       Date:  2001-10-23       Impact factor: 9.910

4.  TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration.

Authors:  Zhaohui Shao; Jeffrey L Browning; Xinhua Lee; Martin L Scott; Sveltlana Shulga-Morskaya; Norm Allaire; Greg Thill; Melissa Levesque; Dinah Sah; John M McCoy; Beth Murray; Vincent Jung; R Blake Pepinsky; Sha Mi
Journal:  Neuron       Date:  2005-02-03       Impact factor: 17.173

5.  LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex.

Authors:  Laura Carim-Todd; Mònica Escarceller; Xavier Estivill; Lauro Sumoy
Journal:  Eur J Neurosci       Date:  2003-12       Impact factor: 3.386

6.  Variant in the sequence of the LINGO1 gene confers risk of essential tremor.

Authors:  Hreinn Stefansson; Stacy Steinberg; Hjorvar Petursson; Omar Gustafsson; Iris H Gudjonsdottir; Gudrun A Jonsdottir; Stefan T Palsson; Thorlakur Jonsson; Jona Saemundsdottir; Gyda Bjornsdottir; Yvonne Böttcher; Theodora Thorlacius; Dietrich Haubenberger; Alexander Zimprich; Eduard Auff; Christoph Hotzy; Claudia M Testa; Lisa A Miyatake; Ami R Rosen; Kristleifur Kristleifsson; David Rye; Friedrich Asmus; Ludger Schöls; Martin Dichgans; Finnbogi Jakobsson; John Benedikz; Unnur Thorsteinsdottir; Jeffrey Gulcher; Augustine Kong; Kari Stefansson
Journal:  Nat Genet       Date:  2009-02-01       Impact factor: 38.330

7.  New data on the genetics of Parkinson's disease.

Authors:  A Barbeau; E Pourcher
Journal:  Can J Neurol Sci       Date:  1982-02       Impact factor: 2.104

8.  Neuropathological changes in essential tremor: 33 cases compared with 21 controls.

Authors:  Elan D Louis; Phyllis L Faust; Jean-Paul G Vonsattel; Lawrence S Honig; Alex Rajput; Christopher A Robinson; Ali Rajput; Rajesh Pahwa; Kelly E Lyons; G Webster Ross; Sarah Borden; Carol B Moskowitz; Arlene Lawton; Nora Hernandez
Journal:  Brain       Date:  2007-11-19       Impact factor: 13.501

9.  LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis.

Authors:  Sha Mi; Bing Hu; Kyungmin Hahm; Yi Luo; Edward Sai Kam Hui; Qiuju Yuan; Wai Man Wong; Li Wang; Huanxing Su; Tak-Ho Chu; Jiasong Guo; Wenming Zhang; Kwok-Fai So; Blake Pepinsky; Zhaohui Shao; Christilyn Graff; Ellen Garber; Vincent Jung; Ed Xuekui Wu; Wutian Wu
Journal:  Nat Med       Date:  2007-09-30       Impact factor: 53.440

10.  Genomewide association study for susceptibility genes contributing to familial Parkinson disease.

Authors:  Nathan Pankratz; Jemma B Wilk; Jeanne C Latourelle; Anita L DeStefano; Cheryl Halter; Elizabeth W Pugh; Kimberly F Doheny; James F Gusella; William C Nichols; Tatiana Foroud; Richard H Myers
Journal:  Hum Genet       Date:  2008-11-06       Impact factor: 4.132
View more
  26 in total

1.  LINGO1 and essential tremor: linking the shakes. Linking LINGO1 to essential tremor.

Authors:  Eng-King Tan
Journal:  Eur J Hum Genet       Date:  2010-04-07       Impact factor: 4.246

2.  Replication of the LINGO1 gene association with essential tremor in a North American population.

Authors:  Lorraine N Clark; Naeun Park; Sergey Kisselev; Eileen Rios; Joseph H Lee; Elan D Louis
Journal:  Eur J Hum Genet       Date:  2010-04-07       Impact factor: 4.246

3.  Lingo2 variants associated with essential tremor and Parkinson's disease.

Authors:  Yi-Wen Wu; K M Prakash; Tian-Yi Rong; Hui-Hua Li; Qin Xiao; Louis C Tan; Wing-Lok Au; Jian-qing Ding; Sheng-di Chen; Eng-King Tan
Journal:  Hum Genet       Date:  2011-02-02       Impact factor: 4.132

4.  Genetic analysis of the leucine-rich repeat and lg domain containing Nogo receptor-interacting protein 1 gene in essential tremor.

Authors:  Hui Liang; Zhi Song; Xiong Deng; Hongbo Xu; Anding Zhu; Wen Zheng; Yongxiang Zhao; Hao Deng
Journal:  J Mol Neurosci       Date:  2013-06-12       Impact factor: 3.444

Review 5.  Challenges in essential tremor genetics.

Authors:  L N Clark; E D Louis
Journal:  Rev Neurol (Paris)       Date:  2015-05-21       Impact factor: 2.607

6.  Lingo-1 expression is increased in essential tremor cerebellum and is present in the basket cell pinceau.

Authors:  Sheng-Han Kuo; Guomei Tang; Elan D Louis; Karen Ma; Rachel Babji; Matthew Balatbat; Etty Cortes; Jean-Paul G Vonsattel; Ai Yamamoto; David Sulzer; Phyllis L Faust
Journal:  Acta Neuropathol       Date:  2013-03-31       Impact factor: 17.088

Review 7.  Genetics of Parkinson disease and essential tremor.

Authors:  Christian Wider; Owen A Ross; Zbigniew K Wszolek
Journal:  Curr Opin Neurol       Date:  2010-08       Impact factor: 5.710

8.  LINGO1 and LINGO2 variants are associated with essential tremor and Parkinson disease.

Authors:  Carles Vilariño-Güell; Christian Wider; Owen A Ross; Barbara Jasinska-Myga; Jennifer Kachergus; Stephanie A Cobb; Alexandra I Soto-Ortolaza; Bahareh Behrouz; Michael G Heckman; Nancy N Diehl; Claudia M Testa; Zbigniew K Wszolek; Ryan J Uitti; Joseph Jankovic; Elan D Louis; Lorraine N Clark; Alex Rajput; Matthew J Farrer
Journal:  Neurogenetics       Date:  2010-04-06       Impact factor: 2.660

Review 9.  Essential tremor.

Authors:  Lorraine N Clark; Elan D Louis
Journal:  Handb Clin Neurol       Date:  2018

10.  Analysis and meta-analysis of five polymorphisms of the LINGO1 and LINGO2 genes in Parkinson's disease and multiple system atrophy in a Chinese population.

Authors:  YongPing Chen; Bei Cao; Jing Yang; QianQian Wei; Ru Wei Ou; Bi Zhao; Wei Song; XiaoYan Guo; HuiFang Shang
Journal:  J Neurol       Date:  2015-08-08       Impact factor: 4.849
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.