Literature DB >> 19719208

Zn(II)-Catalyzed synthesis of piperidines from propargyl amines and cyclopropanes.

Terry P Lebold1, Andrew B Leduc, Michael A Kerr.   

Abstract

The reaction of benzyl-protected propargyl amines and 1,1-cyclopropane diesters in the presence of catalytic Zn(NTf(2))(2) allows access to highly functionalized piperidines in excellent yields. The process proceeds via a tandem cyclopropane ring-opening/Conia-ene cyclization.

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Year:  2009        PMID： 19719208     DOI： 10.1021/ol901435k

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Polarity inversion of donor-acceptor cyclopropanes: disubstituted δ-lactones via enantioselective iridium catalysis.

Authors:  Joseph Moran; Austin G Smith; Ryan M Carris; Jeffrey S Johnson; Michael J Krische
Journal:  J Am Chem Soc       Date:  2011-10-31       Impact factor: 15.419

2.  One-Pot Catalytic Asymmetric Synthesis of Tetrahydrocarbazoles.

Authors:  Qiong-Jie Liu; Wen-Guang Yan; Lijia Wang; X Peter Zhang; Yong Tang
Journal:  Org Lett       Date:  2015-08-07       Impact factor: 6.005

3.  PEG-embedded KBr(3): A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines.

Authors:  Sanny Verma; Suman L Jain; Bir Sain
Journal:  Beilstein J Org Chem       Date:  2011-09-28       Impact factor: 2.883

Review 4.  N-tert-Butanesulfinyl imines in the asymmetric synthesis of nitrogen-containing heterocycles.

Authors:  Joseane A Mendes; Paulo R R Costa; Miguel Yus; Francisco Foubelo; Camilla D Buarque
Journal:  Beilstein J Org Chem       Date:  2021-05-12       Impact factor: 2.883
  4 in total

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