Literature DB >> 19716505

Impact of xerostomia on the quality of life of adolescents with type 1 diabetes mellitus.

Ivana Maria Saes Busato1, Sérgio Aparecido Ignácio, João Armando Brancher, Ana Maria Trindade Grégio, Maria Angela Naval Machado, Luciana Reis Azevedo-Alanis.   

Abstract

OBJECTIVE: To evaluate the impact of xerostomia on the quality of life (QOL) of adolescents with type 1 diabetes mellitus (DM1). STUDY
DESIGN: The sample was comprised of 51 adolescents with DM1. Diabetic status was determined by glycosylated hemoglobin (HbG) and capillary glucose (CG) tests. Poor metabolic control was defined as HbG >8.0% and CG <90 mg/dL or >130 mg/dL. Measurement of salivary flow was performed by means of stimulated saliva collection. Xerostomia was detected by asking a question about the sensation of having "dry mouth," and OHIP-14 was used to measure the impact of xerostomia on QOL.
RESULTS: A total of 52.9% of subjects presented with xerostomia and 40.8% with hyposalivation. Significant differences between the subjects with and without xerostomia regarding metabolic control levels were not observed (P > .05). However, OHIP-14 scores were significantly different between the subjects with and without xerostomia (P < .001).
CONCLUSIONS: Xerostomia is frequent and has a negative impact on QOL of adolescents with DM1.

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Year:  2009        PMID: 19716505     DOI: 10.1016/j.tripleo.2009.05.005

Source DB:  PubMed          Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod        ISSN: 1079-2104


  7 in total

1.  Integrating genomic data from high-throughput studies with computational modeling reveals differences in the molecular basis of hyposalivation between type 1 and type 2 diabetes.

Authors:  Nili Tickotsky; Yanay Ofran
Journal:  Clin Oral Investig       Date:  2017-03-03       Impact factor: 3.573

2.  Downregulation of Salivary Proteins, Protective against Dental Caries, in Type 1 Diabetes.

Authors:  Eftychia Pappa; Konstantinos Vougas; Jerome Zoidakis; William Papaioannou; Christos Rahiotis; Heleni Vastardis
Journal:  Proteomes       Date:  2021-07-19

3.  Maxillary rehabilitation of periodontally compromised patients with extensive one-piece fixed prostheses supported by natural teeth: a retrospective longitudinal study.

Authors:  Alexander Heschl; Michael Haas; Josef Haas; Michael Payer; Walther Wegscheider; Raoul Polansky
Journal:  Clin Oral Investig       Date:  2013-01       Impact factor: 3.573

Review 4.  Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage.

Authors:  Roberto Pinna; Guglielmo Campus; Enzo Cumbo; Ida Mura; Egle Milia
Journal:  Ther Clin Risk Manag       Date:  2015-02-04       Impact factor: 2.423

Review 5.  Xerostomia due to systemic disease: a review of 20 conditions and mechanisms.

Authors:  H Mortazavi; M Baharvand; A Movahhedian; M Mohammadi; A Khodadoustan
Journal:  Ann Med Health Sci Res       Date:  2014-07

6.  The effect of xerostomia and hyposalivation on the quality of life of patients with type II diabetes mellitus.

Authors:  Tahereh Molania; Mona Alimohammadi; Ozra Akha; Jaber Mousavi; Ramin Razvini; Maedeh Salehi
Journal:  Electron Physician       Date:  2017-11-25

7.  Oral conditions and salivary analysis in HIV-uninfected subjects using preexposure prophylaxis.

Authors:  N Macedo; G Baggio; I Henn; J Santos; T Batista; S Ignácio; P Souza; L Azevedo-Alanis
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2022-05-01
  7 in total

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