Literature DB >> 19716086

Is it time to develop a "pathogenicity" score to distinguish long QT syndrome causing mutations from "background" genetic noise?

Dawood Darbar.   

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Year:  2009        PMID： 19716086      PMCID： PMC2758102          DOI： 10.1016/j.hrthm.2009.06.027

Source DB:  PubMed          Journal:  Heart Rhythm        ISSN： 1547-5271            Impact factor:   6.343


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  21 in total

1.  Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.

Authors:  P J Schwartz; S G Priori; C Spazzolini; A J Moss; G M Vincent; C Napolitano; I Denjoy; P Guicheney; G Breithardt; M T Keating; J A Towbin; A H Beggs; P Brink; A A Wilde; L Toivonen; W Zareba; J L Robinson; K W Timothy; V Corfield; D Wattanasirichaigoon; C Corbett; W Haverkamp; E Schulze-Bahr; M H Lehmann; K Schwartz; P Coumel; R Bloise
Journal:  Circulation       Date:  2001-01-02       Impact factor: 29.690

2.  Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome.

Authors:  A J Moss; W Zareba; W J Hall; P J Schwartz; R S Crampton; J Benhorin; G M Vincent; E H Locati; S G Priori; C Napolitano; A Medina; L Zhang; J L Robinson; K Timothy; J A Towbin; M L Andrews
Journal:  Circulation       Date:  2000-02-15       Impact factor: 29.690

3.  Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death.

Authors:  Peter J Mohler; Jean-Jacques Schott; Anthony O Gramolini; Keith W Dilly; Silvia Guatimosim; William H duBell; Long-Sheng Song; Karine Haurogné; Florence Kyndt; Mervat E Ali; Terry B Rogers; W J Lederer; Denis Escande; Herve Le Marec; Vann Bennett
Journal:  Nature       Date:  2003-02-06       Impact factor: 49.962

4.  Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.

Authors:  Igor Splawski; Katherine W Timothy; Leah M Sharpe; Niels Decher; Pradeep Kumar; Raffaella Bloise; Carlo Napolitano; Peter J Schwartz; Robert M Joseph; Karen Condouris; Helen Tager-Flusberg; Silvia G Priori; Michael C Sanguinetti; Mark T Keating
Journal:  Cell       Date:  2004-10-01       Impact factor: 41.582

5.  Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias.

Authors:  Q Wang; M E Curran; I Splawski; T C Burn; J M Millholland; T J VanRaay; J Shen; K W Timothy; G M Vincent; T de Jager; P J Schwartz; J A Toubin; A J Moss; D L Atkinson; G M Landes; T D Connors; M T Keating
Journal:  Nat Genet       Date:  1996-01       Impact factor: 38.330

6.  ECG T-wave patterns in genetically distinct forms of the hereditary long QT syndrome.

Authors:  A J Moss; W Zareba; J Benhorin; E H Locati; W J Hall; J L Robinson; P J Schwartz; J A Towbin; G M Vincent; M H Lehmann
Journal:  Circulation       Date:  1995-11-15       Impact factor: 29.690

7.  SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome.

Authors:  Q Wang; J Shen; I Splawski; D Atkinson; Z Li; J L Robinson; A J Moss; J A Towbin; M T Keating
Journal:  Cell       Date:  1995-03-10       Impact factor: 41.582

8.  A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome.

Authors:  M E Curran; I Splawski; K W Timothy; G M Vincent; E D Green; M T Keating
Journal:  Cell       Date:  1995-03-10       Impact factor: 41.582

9.  Gene-specific response of dynamic ventricular repolarization to sympathetic stimulation in LQT1, LQT2 and LQT3 forms of congenital long QT syndrome.

Authors:  T Noda; H Takaki; T Kurita; K Suyama; N Nagaya; A Taguchi; N Aihara; S Kamakura; K Sunagawa; K Nakamura; T Ohe; M Horie; C Napolitano; J A Towbin; S G Priori; W Shimizu
Journal:  Eur Heart J       Date:  2002-06       Impact factor: 29.983

10.  Risk stratification in the long-QT syndrome.

Authors:  Silvia G Priori; Peter J Schwartz; Carlo Napolitano; Raffaella Bloise; Elena Ronchetti; Massimiliano Grillo; Alessandro Vicentini; Carla Spazzolini; Janni Nastoli; Georgia Bottelli; Roberta Folli; Donata Cappelletti
Journal:  N Engl J Med       Date:  2003-05-08       Impact factor: 91.245
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  5 in total

Review 1.  The Role of Pharmacogenetics in Atrial Fibrillation Therapeutics: Is Personalized Therapy in Sight?

Authors:  Dawood Darbar
Journal:  J Cardiovasc Pharmacol       Date:  2016-01       Impact factor: 3.105

2.  Impact of gene patents and licensing practices on access to genetic testing for long QT syndrome.

Authors:  Misha Angrist; Subhashini Chandrasekharan; Christopher Heaney; Robert Cook-Deegan
Journal:  Genet Med       Date:  2010-04       Impact factor: 8.864

3.  Association of QTc Interval and V4-S Wave With Appropriate ICD Therapy in Hypertrophic Cardiomyopathy.

Authors:  Nixiao Zhang; Sijing Cheng; Hongxia Niu; Min Gu; Hui Peng; Zhijun Sun; Xi Liu; Yu Deng; Xuhua Chen; Wei Hua
Journal:  Front Cardiovasc Med       Date:  2022-05-12

4.  Atrial Fibrillation and SCN5A Variants.

Authors:  Eleonora Savio-Galimberti; Dawood Darbar
Journal:  Card Electrophysiol Clin       Date:  2014-12-01

5.  SCN10A/Nav1.8 modulation of peak and late sodium currents in patients with early onset atrial fibrillation.

Authors:  Eleonora Savio-Galimberti; Peter Weeke; Raafia Muhammad; Marcia Blair; Sami Ansari; Laura Short; Thomas C Atack; Kaylen Kor; Carlos G Vanoye; Morten Salling Olesen; Tao Yang; Alfred L George; Dan M Roden; Dawood Darbar
Journal:  Cardiovasc Res       Date:  2014-07-22       Impact factor: 10.787
  5 in total

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