OBJECTIVES: This study evaluated the immediate and 3 month clinical effects of a low-level gallium-aluminum-arsenide (GaAlAs) laser and a 3% potassium oxalate gel for the treatment of dentinal hypersensitivity. MATERIALS AND METHODS:A total of 164 teeth from 30 patients with clinical diagnoses of dentinal hypersensitivity were selected for this randomized, placebo-controlled, double-blind clinical study. The teeth were randomized to three groups: GaAlAs laser, oxalate gel, and placebo gel. The treatment sessions were performed at 7 d intervals for four consecutive weeks. The degree of sensitivity in response to an air blast and tactile stimuli was assessed according to a visual analogue scale at baseline, immediately after the fourth application, and then 3 months after the fourth application. The reductions in dentinal hypersensitivity from baseline at the two follow-up assessments were evaluated as the main outcome. RESULTS: In both the active and control groups, there were statistically significant reductions in dentinal hypersensitivity immediately after and 3 months after the treatments, when compared with the hypersensitivity at baseline. No significant differences among the three groups could be detected in their efficacy at either the immediate or 3 month evaluations irrespective of the stimulus. CONCLUSIONS: The treatments under study were effective for reducing dentinal hypersensitivity, and longer observational periods could enhance the ability of studies to detect differences between active and placebo groups.
RCT Entities:
OBJECTIVES: This study evaluated the immediate and 3 month clinical effects of a low-level gallium-aluminum-arsenide (GaAlAs) laser and a 3% potassium oxalate gel for the treatment of dentinal hypersensitivity. MATERIALS AND METHODS: A total of 164 teeth from 30 patients with clinical diagnoses of dentinal hypersensitivity were selected for this randomized, placebo-controlled, double-blind clinical study. The teeth were randomized to three groups: GaAlAs laser, oxalate gel, and placebo gel. The treatment sessions were performed at 7 d intervals for four consecutive weeks. The degree of sensitivity in response to an air blast and tactile stimuli was assessed according to a visual analogue scale at baseline, immediately after the fourth application, and then 3 months after the fourth application. The reductions in dentinal hypersensitivity from baseline at the two follow-up assessments were evaluated as the main outcome. RESULTS: In both the active and control groups, there were statistically significant reductions in dentinal hypersensitivity immediately after and 3 months after the treatments, when compared with the hypersensitivity at baseline. No significant differences among the three groups could be detected in their efficacy at either the immediate or 3 month evaluations irrespective of the stimulus. CONCLUSIONS: The treatments under study were effective for reducing dentinal hypersensitivity, and longer observational periods could enhance the ability of studies to detect differences between active and placebo groups.
Authors: Nadine Luísa Guimarães Albuquerque; André Mattos Brito de Souza; Maria Denise Rodrigues de Moraes; Juliano Sartori Mendonça; Lidiany Karla Azevedo Rodrigues; Sérgio Lima Santiago Journal: Clin Oral Investig Date: 2015-07-15 Impact factor: 3.573
Authors: Alana Cristina Machado; Ítallo Emídio Lira Viana; Aloisio Melo Farias-Neto; Mariana Minatel Braga; Carlos de Paula Eduardo; Patricia Moreira de Freitas; Ana Cecilia Corrêa Aranha Journal: Lasers Med Sci Date: 2017-12-05 Impact factor: 3.161