Literature DB >> 19708915

Hear the Wnt Ror: how melanoma cells adjust to changes in Wnt.

Michael P O'Connell1, Ashani T Weeraratna.   

Abstract

The interplay between canonical and non-canonical Wnt pathways in development and tumorigenesis is tightly regulated. In this review we will describe the yin and the yang of canonical and non-canonical Wnt signaling pathways during melanocyte development, and melanoma genesis. Canonical Wnt signaling, represented by Wnts such as Wnt1 and Wnt3A, signals via beta-catenin to promote melanocyte differentiation and tumor development. Non-canonical Wnt signaling, specifically Wnt5A, regulates canonical pathways, and signals to induce melanoma metastasis. This review will focus on the role of Wnt5A during melanoma progression, and its relationship to canonical Wnt signaling.

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Year:  2009        PMID： 19708915      PMCID： PMC2766021          DOI： 10.1111/j.1755-148X.2009.00627.x

Source DB:  PubMed          Journal:  Pigment Cell Melanoma Res        ISSN： 1755-1471            Impact factor:   4.693


  153 in total

1.  Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad.

Authors:  Katherine Jeays-Ward; Christine Hoyle; Jennifer Brennan; Mathieu Dandonneau; Graham Alldus; Blanche Capel; Amanda Swain
Journal:  Development       Date:  2003-08       Impact factor: 6.868

2.  The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway.

Authors:  Isao Oishi; Hiroaki Suzuki; Nobuyuki Onishi; Ritsuko Takada; Shuichi Kani; Bisei Ohkawara; Ikue Koshida; Kentaro Suzuki; General Yamada; Georg C Schwabe; Stefan Mundlos; Hiroshi Shibuya; Shinji Takada; Yasuhiro Minami
Journal:  Genes Cells       Date:  2003-07       Impact factor: 1.891

3.  Down-regulation of Wnt-4 and up-regulation of Wnt-5a expression by epithelial-mesenchymal transition in human squamous carcinoma cells.

Authors:  Masayuki Taki; Nobuyuki Kamata; Kazuhiro Yokoyama; Ryoichi Fujimoto; Satoshi Tsutsumi; Masaru Nagayama
Journal:  Cancer Sci       Date:  2003-07       Impact factor: 6.716

4.  Regulation of casein kinase I epsilon activity by Wnt signaling.

Authors:  Wojciech Swiatek; I-Chun Tsai; Laura Klimowski; Andrea Pepler; Janet Barnette; H Joseph Yost; David M Virshup
Journal:  J Biol Chem       Date:  2004-01-13       Impact factor: 5.157

5.  BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma.

Authors:  Jianli Dong; Robert G Phelps; Rui Qiao; Shen Yao; Outhiriaradjou Benard; Zeev Ronai; Stuart A Aaronson
Journal:  Cancer Res       Date:  2003-07-15       Impact factor: 12.701

6.  The human Frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt. beta-catenin signaling cascade.

Authors:  Tamar Golan; Abraham Yaniv; Anna Bafico; Guizhong Liu; Arnona Gazit
Journal:  J Biol Chem       Date:  2004-01-27       Impact factor: 5.157

7.  Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation.

Authors:  Markus Morkel; Joerg Huelsken; Maki Wakamiya; Jixiang Ding; Marc van de Wetering; Hans Clevers; Makoto M Taketo; Richard R Behringer; Michael M Shen; Walter Birchmeier
Journal:  Development       Date:  2003-12       Impact factor: 6.868

8.  CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin.

Authors:  Adela R Cardones; Takashi Murakami; Sam T Hwang
Journal:  Cancer Res       Date:  2003-10-15       Impact factor: 12.701

9.  Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity.

Authors:  Trudi A Westfall; Ryan Brimeyer; Jen Twedt; Jean Gladon; Andrea Olberding; Makoto Furutani-Seiki; Diane C Slusarski
Journal:  J Cell Biol       Date:  2003-09-01       Impact factor: 10.539

10.  Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation.

Authors:  Lilia Topol; Xueyuan Jiang; Hosoon Choi; Lisa Garrett-Beal; Peter J Carolan; Yingzi Yang
Journal:  J Cell Biol       Date:  2003-09-01       Impact factor: 10.539
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  41 in total

1.  DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin.

Authors:  A Mitra; M E Menezes; L K Pannell; M S Mulekar; R E Honkanen; L A Shevde; R S Samant
Journal:  Oncogene       Date:  2012-01-23       Impact factor: 9.867

Review 2.  Wnt signaling in mammary glands: plastic cell fates and combinatorial signaling.

Authors:  Caroline M Alexander; Shruti Goel; Saja A Fakhraldeen; Soyoung Kim
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-10-01       Impact factor: 10.005

3.  Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy.

Authors:  Alisha Holtzhausen; Fei Zhao; Kathy S Evans; Masahito Tsutsui; Ciriana Orabona; Douglas S Tyler; Brent A Hanks
Journal:  Cancer Immunol Res       Date:  2015-06-03       Impact factor: 11.151

4.  Changes in the gene expression profile of A375 human melanoma cells induced by overexpression of multifunctional pigment epithelium-derived factor.

Authors:  Jose L Orgaz; Alberto Benguria; Cristina Sanchez-Martinez; Omar Ladhani; Olga V Volpert; Benilde Jimenez
Journal:  Melanoma Res       Date:  2011-08       Impact factor: 3.599

Review 5.  Striking the target in Wnt-y conditions: intervening in Wnt signaling during cancer progression.

Authors:  Tura C Camilli; Ashani T Weeraratna
Journal:  Biochem Pharmacol       Date:  2010-03-06       Impact factor: 5.858

6.  Coordinated activation of Wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration.

Authors:  Piul Rabbani; Makoto Takeo; WeiChin Chou; Peggy Myung; Marcus Bosenberg; Lynda Chin; M Mark Taketo; Mayumi Ito
Journal:  Cell       Date:  2011-06-10       Impact factor: 41.582

7.  Tyrosine phosphatase PTPRD suppresses colon cancer cell migration in coordination with CD44.

Authors:  Kosuke Funato; Yusuke Yamazumi; Takeaki Oda; Tetsu Akiyama
Journal:  Exp Ther Med       Date:  2011-03-21       Impact factor: 2.447

8.  Nucleosome remodeler SNF2L suppresses cell proliferation and migration and attenuates Wnt signaling.

Authors:  Maren Eckey; Silke Kuphal; Tobias Straub; Petra Rümmele; Elisabeth Kremmer; Anja K Bosserhoff; Peter B Becker
Journal:  Mol Cell Biol       Date:  2012-04-16       Impact factor: 4.272

9.  Activation of the canonical Wnt/β-catenin signalling pathway is rare in canine malignant melanoma tissue and cell lines.

Authors:  E Chon; V Thompson; S Schmid; T J Stein
Journal:  J Comp Pathol       Date:  2012-08-14       Impact factor: 1.311

10.  Subcellular trafficking and transfection efficacy of polyethylenimine-polyethylene glycol polyplex nanoparticles with a ligand to melanocortin receptor-1.

Authors:  Mikhail O Durymanov; Elena A Beletkaia; Alexey V Ulasov; Yuri V Khramtsov; Georgiy A Trusov; Nikita S Rodichenko; Tatiana A Slastnikova; Tatiana V Vinogradova; Natalia Y Uspenskaya; Eugene P Kopantsev; Andrey A Rosenkranz; Eugene D Sverdlov; Alexander S Sobolev
Journal:  J Control Release       Date:  2012-09-01       Impact factor: 9.776
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