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Literature DB >> 19701197

Neurod1 is essential for the survival and maturation of adult-born neurons.

Zhengliang Gao¹, Kerstin Ure, Jessica L Ables, Diane C Lagace, Klaus-Armin Nave, Sandra Goebbels, Amelia J Eisch, Jenny Hsieh.

Abstract

The transcriptional program that controls adult neurogenesis is unknown. We generated mice with an inducible stem cell-specific deletion of Neurod1, resulting in substantially fewer newborn neurons in the hippocampus and olfactory bulb. Thus, Neurod1 is cell-intrinsically required for the survival and maturation of adult-born neurons.

Entities: Chemical Disease Gene Mutation Species

Mesh：

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Year: 2009 PMID： 19701197 PMCID： PMC3365543 DOI： 10.1038/nn.2385

Source DB: PubMed Journal: Nat Neurosci ISSN： 1097-6256 Impact factor: 24.884

12 in total

1. Unique expression patterns of cell fate molecules delineate sequential stages of dentate gyrus development.

Authors: S J Pleasure; A E Collins; D H Lowenstein
Journal: J Neurosci Date: 2000-08-15 Impact factor: 6.167

2. Visualization of neurogenesis in the central nervous system using nestin promoter-GFP transgenic mice.

Authors: M Yamaguchi; H Saito; M Suzuki; K Mori
Journal: Neuroreport Date: 2000-06-26 Impact factor: 1.837

3. A CaMKII-NeuroD signaling pathway specifies dendritic morphogenesis.

Authors: Brice Gaudillière; Yoshiyuki Konishi; Núria de la Iglesia; Gui lan Yao; Azad Bonni
Journal: Neuron Date: 2004-01-22 Impact factor: 17.173

4. Excitation-neurogenesis coupling in adult neural stem/progenitor cells.

Authors: Karl Deisseroth; Sheela Singla; Hiroki Toda; Michelle Monje; Theo D Palmer; Robert C Malenka
Journal: Neuron Date: 2004-05-27 Impact factor: 17.173

5. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice.

Authors: F J Naya; H P Huang; Y Qiu; H Mutoh; F J DeMayo; A B Leiter; M J Tsai
Journal: Genes Dev Date: 1997-09-15 Impact factor: 11.361

6. Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus.

Authors: M H Schwab; A Bartholomae; B Heimrich; D Feldmeyer; S Druffel-Augustin; S Goebbels; F J Naya; S Zhao; M Frotscher; M J Tsai; K A Nave
Journal: J Neurosci Date: 2000-05-15 Impact factor: 6.167

7. Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor.

Authors: F J Naya; C M Stellrecht; M J Tsai
Journal: Genes Dev Date: 1995-04-15 Impact factor: 11.361

8. Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2.

Authors: Sandra Goebbels; Ulli Bode; Alexander Pieper; Ursula Funfschilling; Markus H Schwab; Klaus-Armin Nave
Journal: Genesis Date: 2005-08 Impact factor: 2.487

9. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein.

Authors: J E Lee; S M Hollenberg; L Snider; D L Turner; N Lipnick; H Weintraub
Journal: Science Date: 1995-05-12 Impact factor: 47.728

10. Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis.

Authors: Tomoko Kuwabara; Jenny Hsieh; Alysson Muotri; Gene Yeo; Masaki Warashina; Dieter Chichung Lie; Lynne Moore; Kinichi Nakashima; Makoto Asashima; Fred H Gage
Journal: Nat Neurosci Date: 2009-08-23 Impact factor: 24.884

203 in total

1. Wnts influence the timing and efficiency of oligodendrocyte precursor cell generation in the telencephalon.

Authors: Abraham J Langseth; Roeben N Munji; Youngshik Choe; Trung Huynh; Christine D Pozniak; Samuel J Pleasure
Journal: J Neurosci Date: 2010-10-06 Impact factor: 6.167

2. Aging brain microenvironment decreases hippocampal neurogenesis through Wnt-mediated survivin signaling.

Authors: Carlos J Miranda; Lyndsey Braun; Yuying Jiang; Mark E Hester; Ling Zhang; Matthew Riolo; Haijuan Wang; Meghan Rao; Rachel A Altura; Brian K Kaspar
Journal: Aging Cell Date: 2012-04-04 Impact factor: 9.304

Review 3. Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: unraveling the genome to understand the mind.

Authors: Jenny Hsieh; Amelia J Eisch
Journal: Neurobiol Dis Date: 2010-01-28 Impact factor: 5.996

4. RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus.

Authors: Oliver Ehm; Christian Göritz; Marcela Covic; Iris Schäffner; Tobias J Schwarz; Esra Karaca; Bettina Kempkes; Elisabeth Kremmer; Frank W Pfrieger; Lluis Espinosa; Anna Bigas; Claudio Giachino; Verdon Taylor; Jonas Frisén; D Chichung Lie
Journal: J Neurosci Date: 2010-10-13 Impact factor: 6.167

Review 5. The interesting interplay between interneurons and adult hippocampal neurogenesis.

Authors: Irene Masiulis; Sanghee Yun; Amelia J Eisch
Journal: Mol Neurobiol Date: 2011-09-29 Impact factor: 5.590

6. Inducible and conditional deletion of extracellular signal-regulated kinase 5 disrupts adult hippocampal neurogenesis.

Authors: Yung-Wei Pan; Junhui Zou; Wenbin Wang; Hiroyuki Sakagami; Michael G Garelick; Glen Abel; Chay T Kuo; Daniel R Storm; Zhengui Xia
Journal: J Biol Chem Date: 2012-05-29 Impact factor: 5.157