Literature DB >> 19695313

Two 22S-solanidine-type steroidal alkaloids from Fritillaria anhuiensis.

Qing Yao Shou1, Qing Tan, Zheng Wu Shen.   

Abstract

Phytochemical investigation of the fresh bulbs of Fritillaria anhuiensis S. C. Chen et S. E. Yin, resulted in the isolation of a known steroidal alkaloid solanidine of (22S,25S)-solanid-5-en-3beta-ol (1), which has never yet been found as a natural substance, and of a new steroidal alkaloid (22S,25S)-solanid-5,20(21)-dien-3beta-ol. Compounds 1 and 2 were the first solanidine-type alkaloids with 22-S configuration discovered from nature. Their structures were elucidated based on spectroscopic analysis, including 1D and 2D NMR experiments. 2009 Elsevier B.V. All rights reserved.

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Year:  2009        PMID: 19695313     DOI: 10.1016/j.fitote.2009.08.017

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  3 in total

1.  Isolation and Identification of 3,4-Seco-Solanidine-3,4-dioic acid (SSDA) as a Urinary Biomarker of Cytochrome P450 2D6 (CYP2D6) Activity.

Authors:  Andrew C Behrle; Justin Douglas; J Steven Leeder; Leon van Haandel
Journal:  Drug Metab Dispos       Date:  2022-07-25       Impact factor: 3.579

Review 2.  Chemistry and bioactivities of natural steroidal alkaloids.

Authors:  Mei-Ling Xiang; Bin-Yuan Hu; Zi-Heng Qi; Xiao-Na Wang; Tian-Zhen Xie; Zhao-Jie Wang; Dan-Yu Ma; Qi Zeng; Xiao-Dong Luo
Journal:  Nat Prod Bioprospect       Date:  2022-06-15

Review 3.  Natural drug sources for respiratory diseases from Fritillaria: chemical and biological analyses.

Authors:  Ye Wang; Hongping Hou; Qiang Ren; Haoyu Hu; Tiechui Yang; Xiwen Li
Journal:  Chin Med       Date:  2021-05-31       Impact factor: 5.455

  3 in total

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