Literature DB >> 19694441

H/D exchange and mass spectrometry in the studies of protein conformation and dynamics: is there a need for a top-down approach?

Igor A Kaltashov1, Cedric E Bobst, Rinat R Abzalimov.   

Abstract

Hydrogen/deuterium exchange (HDX) combined with mass spectrometry (MS) detection has matured in recent years to become a powerful tool in structural biology and biophysics. Several limitations of this technique can and will be addressed by tapping into the ever expanding arsenal of methods to manipulate ions in the gas phase offered by mass spectrometry.

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Year:  2009        PMID： 19694441      PMCID： PMC2805115          DOI： 10.1021/ac901366n

Source DB:  PubMed          Journal:  Anal Chem        ISSN： 0003-2700            Impact factor:   6.986


  39 in total

Review 1.  Protein-folding kinetics and mechanisms studied by pulse-labeling and mass spectrometry.

Authors:  Lars Konermann; Douglas A Simmons
Journal:  Mass Spectrom Rev       Date:  2003 Jan-Feb       Impact factor: 10.946

Review 2.  From words to literature in structural proteomics.

Authors:  Andrej Sali; Robert Glaeser; Thomas Earnest; Wolfgang Baumeister
Journal:  Nature       Date:  2003-03-13       Impact factor: 49.962

3.  Is there hydrogen scrambling in the gas phase? Energetic and structural determinants of proton mobility within protein ions.

Authors:  Joshua K Hoerner; Hui Xiao; Andras Dobo; Igor A Kaltashov
Journal:  J Am Chem Soc       Date:  2004-06-23       Impact factor: 15.419

4.  Do ionic charges in ESI MS provide useful information on macromolecular structure?

Authors:  Igor A Kaltashov; Rinat R Abzalimov
Journal:  J Am Soc Mass Spectrom       Date:  2008-07-03       Impact factor: 3.109

Review 5.  The molecular sociology of the cell.

Authors:  Carol V Robinson; Andrej Sali; Wolfgang Baumeister
Journal:  Nature       Date:  2007-12-13       Impact factor: 49.962

6.  Unfolding dynamics of a beta-sheet protein studied by mass spectrometry.

Authors:  S J Eyles; T Dresch; L M Gierasch; I A Kaltashov
Journal:  J Mass Spectrom       Date:  1999-12       Impact factor: 1.982

Review 7.  Investigation of protein folding by mass spectrometry.

Authors:  A Miranker; C V Robinson; S E Radford; C M Dobson
Journal:  FASEB J       Date:  1996-01       Impact factor: 5.191

8.  Sequence-specific conformational flexibility of SNARE transmembrane helices probed by hydrogen/deuterium exchange.

Authors:  Walter Stelzer; Bernhard C Poschner; Holger Stalz; Albert J Heck; Dieter Langosch
Journal:  Biophys J       Date:  2008-05-02       Impact factor: 4.033

Review 9.  Hydrogen exchange methods to study protein folding.

Authors:  Mallela M G Krishna; Linh Hoang; Yan Lin; S Walter Englander
Journal:  Methods       Date:  2004-09       Impact factor: 3.608

10.  Interaction of group IA phospholipase A2 with metal ions and phospholipid vesicles probed with deuterium exchange mass spectrometry.

Authors:  John E Burke; Mark J Karbarz; Raymond A Deems; Sheng Li; Virgil L Woods; Edward A Dennis
Journal:  Biochemistry       Date:  2008-05-24       Impact factor: 3.162
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  50 in total

1.  New protein footprinting: fast photochemical iodination combined with top-down and bottom-up mass spectrometry.

Authors:  Jiawei Chen; Weidong Cui; Daryl Giblin; Michael L Gross
Journal:  J Am Soc Mass Spectrom       Date:  2012-06-06       Impact factor: 3.109

2.  'Fixed charge' chemical derivatization and data dependant multistage tandem mass spectrometry for mapping protein surface residue accessibility.

Authors:  Xiao Zhou; Yali Lu; Wenjing Wang; Babak Borhan; Gavin E Reid
Journal:  J Am Soc Mass Spectrom       Date:  2010-04-08       Impact factor: 3.109

3.  Elucidating the higher-order structure of biopolymers by structural probing and mass spectrometry: MS3D.

Authors:  Daniele Fabris; Eizadora T Yu
Journal:  J Mass Spectrom       Date:  2010-08       Impact factor: 1.982

4.  ETD in a traveling wave ion guide at tuned Z-spray ion source conditions allows for site-specific hydrogen/deuterium exchange measurements.

Authors:  Kasper D Rand; Steven D Pringle; Michael Morris; John R Engen; Jeffery M Brown
Journal:  J Am Soc Mass Spectrom       Date:  2011-07-09       Impact factor: 3.109

Review 5.  Integrating mass spectrometry of intact protein complexes into structural proteomics.

Authors:  Suk-Joon Hyung; Brandon T Ruotolo
Journal:  Proteomics       Date:  2012-05       Impact factor: 3.984

6.  Conformer-specific characterization of nonnative protein states using hydrogen exchange and top-down mass spectrometry.

Authors:  Guanbo Wang; Rinat R Abzalimov; Cedric E Bobst; Igor A Kaltashov
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-25       Impact factor: 11.205

7.  Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry.

Authors:  Alem W Kahsai; Sudarshan Rajagopal; Jinpeng Sun; Kunhong Xiao
Journal:  Nat Protoc       Date:  2014-05-08       Impact factor: 13.491

8.  Conformation and dynamics of biopharmaceuticals: transition of mass spectrometry-based tools from academe to industry.

Authors:  Igor A Kaltashov; Cedric E Bobst; Rinat R Abzalimov; Steven A Berkowitz; Damian Houde
Journal:  J Am Soc Mass Spectrom       Date:  2009-10-29       Impact factor: 3.109

Review 9.  Mass spectrometry-based methods in characterization of the higher order structure of protein therapeutics.

Authors:  Igor A Kaltashov; Cedric E Bobst; Jake Pawlowski; Guanbo Wang
Journal:  J Pharm Biomed Anal       Date:  2020-02-12       Impact factor: 3.935

10.  Controlling hydrogen scrambling in multiply charged protein ions during collisional activation: implications for top-down hydrogen/deuterium exchange MS utilizing collisional activation in the gas phase.

Authors:  Rinat R Abzalimov; Igor A Kaltashov
Journal:  Anal Chem       Date:  2010-02-01       Impact factor: 6.986
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