Literature DB >> 19692803

Taking up the challenge of measuring prolonged pain in (premature) neonates: the COMFORTneo scale seems promising.

Monique van Dijk1, Daniella W E Roofthooft, Kanwaljeet J S Anand, Fleur Guldemond, Joke de Graaf, Sinno Simons, Youette de Jager, Johannes B van Goudoever, Dick Tibboel.   

Abstract

OBJECTIVES: Pain assessment is essential to tailor intensive care of neonates. The present focus is on acute procedural pain; assessment of pain of longer duration remains a challenge. We therefore tested a modified version of the COMFORT-behavior scale-named COMFORTneo-for its psychometric qualities in the Neonatal Intensive Care Unit setting.
METHODS: In a clinical observational study, nurses assessed patients with COMFORTneo and Numeric Rating Scales (NRS) for pain and distress, respectively. Interrater reliability, concurrent validity, and sensitivity to change were calculated as well as sensitivity and specificity for different cut-off scores for subsets of patients.
RESULTS: Interrater reliability was good: median linearly weighted Cohen kappa 0.79. Almost 3600 triple ratings were obtained for 286 neonates. Internal consistency was good (Cronbach alpha 0.84 and 0.88). Concurrent validity was demonstrated by adequate and good correlations, respectively, with NRS-pain and NRS-distress: r=0.52 (95% confidence interval 0.44-0.59) and r=0.70 (95% confidence interval 0.64-0.75). COMFORTneo cut-off scores of 14 or higher (score range is 6 to 30) had good sensitivity and specificity (0.81 and 0.90, respectively) using NRS-pain or NRS-distress scores of 4 or higher as criterion. DISCUSSION: The COMFORTneo showed preliminary reliability. No major differences were found in cut-off values for low birth weight, small for gestational age, neurologic impairment risk levels, or sex. Multicenter studies should focus on establishing concurrent validity with other instruments in a patient group with a high probability of ongoing pain.

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Year:  2009        PMID: 19692803     DOI: 10.1097/AJP.0b013e3181a5b52a

Source DB:  PubMed          Journal:  Clin J Pain        ISSN: 0749-8047            Impact factor:   3.442


  33 in total

1.  Behavioral Observation of Infants With Life-Threatening or Life-Limiting Illness in the Neonatal Intensive Care Unit.

Authors:  Christine A Fortney; Stephanie D Sealschott; Rita H Pickler
Journal:  Nurs Res       Date:  2020 Sep/Oct       Impact factor: 2.381

2.  [Pain therapy for premature babies and neonates].

Authors:  M Richter; B Seipolt
Journal:  Schmerz       Date:  2018-04       Impact factor: 1.107

3.  Randomized Controlled Trial Comparing Different Single Doses of Intravenous Paracetamol for Placement of Peripherally Inserted Central Catheters in Preterm Infants.

Authors:  Daniella W E Roofthooft; Sinno H P Simons; Richard A van Lingen; Dick Tibboel; John N van den Anker; Irwin K H Reiss; Monique van Dijk
Journal:  Neonatology       Date:  2017-05-31       Impact factor: 4.035

Review 4.  Clonidine for sedation and analgesia for neonates receiving mechanical ventilation.

Authors:  Olga Romantsik; Maria Grazia Calevo; Elisabeth Norman; Matteo Bruschettini
Journal:  Cochrane Database Syst Rev       Date:  2017-05-10

Review 5.  Neonatal Pain: Perceptions and Current Practice.

Authors:  Mallory Perry; Zewen Tan; Jie Chen; Tessa Weidig; Wanli Xu; Xiaomei S Cong
Journal:  Crit Care Nurs Clin North Am       Date:  2018-12       Impact factor: 1.326

Review 6.  Sucrose for analgesia in newborn infants undergoing painful procedures.

Authors:  Bonnie Stevens; Janet Yamada; Arne Ohlsson; Sarah Haliburton; Allyson Shorkey
Journal:  Cochrane Database Syst Rev       Date:  2016-07-16

Review 7.  Paracetamol (acetaminophen) for prevention or treatment of pain in newborns.

Authors:  Arne Ohlsson; Prakeshkumar S Shah
Journal:  Cochrane Database Syst Rev       Date:  2016-10-07

8.  Pharmacokinetics and pharmacodynamics of medication in asphyxiated newborns during controlled hypothermia. The PharmaCool multicenter study.

Authors:  Timo R de Haan; Yuma A Bijleveld; Johanna H van der Lee; Floris Groenendaal; Marcel P H van den Broek; Carin M A Rademaker; Henrica L M van Straaten; Mirjam M van Weissenbruch; Jeroen R Vermeulen; Peter H Dijk; Jeroen Dudink; Monique Rijken; Arno van Heijst; Koen P Dijkman; Danilo Gavilanes; Anton H van Kaam; Martin Offringa; Ron A A Mathôt
Journal:  BMC Pediatr       Date:  2012-05-22       Impact factor: 2.125

9.  Paracetamol (acetaminophen) for prevention or treatment of pain in newborns.

Authors:  Arne Ohlsson; Prakeshkumar S Shah
Journal:  Cochrane Database Syst Rev       Date:  2020-01-27

10.  Opioids for newborn infants receiving mechanical ventilation.

Authors:  Roberto Bellù; Olga Romantsik; Chiara Nava; Koert A de Waal; Rinaldo Zanini; Matteo Bruschettini
Journal:  Cochrane Database Syst Rev       Date:  2021-03-17
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