Literature DB >> 19686923

Prophylactic antiemetics in oral and maxillofacial surgery: a requiem?

Mohan Alexander1, Balasubramanian Krishnan, V Yuvraj.   

Abstract

PURPOSE: To determine the incidence of postoperative nausea and vomiting (PONV) after oral and maxillofacial surgical procedures and to evaluate the rationale behind prophylactic antiemetic medications.
MATERIALS AND METHODS: A total of 167 patients, irrespective of age and gender, undergoing oral and maxillofacial surgical procedures under general anesthesia/dissociative anesthesia, were included. Risk factors associated with PONV such as gender, type of anesthetic agent used, nature of surgical procedure, surgical approach used, and duration of surgery and postoperative use of opioids were assessed. A "watch and wait" policy was adopted in all cases of recorded PONV with gastric lavage (GL) to be performed in patients with more than 2 episodes of PONV in the 6-hour postoperative period. The efficacy of such an intervention was also assessed. Antiemetic medications were given in only those cases which did not respond favorably to GL. A chi(2) test was performed using SPSS software (Chicago, IL) to determine statistical significance.
RESULTS: Of the 167 patients included, 19 patients experienced episodes of PONV. GL was performed in 3 patients, and all showed cessation of emesis after this intervention. No antiemetic medications were administered. A significant association was observed between PONV and female gender, duration of surgery, type of anesthetic agent used, and specific surgical procedures such as oncologic and temporomandibular joint surgeries. The role of surgical approach and the use of opioids in the postoperative period on the incidence of PONV were found to be insignificant.
CONCLUSIONS: Information regarding the incidence of PONV after oral and maxillofacial surgical procedures remains scanty. We conclude that there does not appear to be a rationale for the prophylactic administration of antiemetic drugs in such surgical procedures. A watch-and-wait policy and simple GL may provide significant relief. Antiemetic medications are to be considered only in case of non-responders and intractable PONV.

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Year:  2009        PMID: 19686923     DOI: 10.1016/j.joms.2009.04.094

Source DB:  PubMed          Journal:  J Oral Maxillofac Surg        ISSN: 0278-2391            Impact factor:   1.895


  5 in total

1.  Factors associated to post-operative nausea and vomiting following oral and maxillofacial surgery: a prospective study.

Authors:  Assis Filipe Medeiros Albuquerque; Salomão Israel Monteiro Lourenço Queiroz; Adriano Rocha Germano; José Sandro Pereira da Silva
Journal:  Oral Maxillofac Surg       Date:  2016-11-30

2.  Comparative Evaluation of IV Paracetamol Versus IV Dexmedetomidine in Inpatient Oral and Maxillofacial Surgery: A Double-Blinded Randomized Controlled Study.

Authors:  K Guru; S Adinarayanan; B Krishnan; Satyen Parida; B Hemavathi; Prasanna Udupi Bidkar; K Narmadhalakshmi
Journal:  J Maxillofac Oral Surg       Date:  2019-07-29

3.  Postoperative nausea and vomiting after general anesthesia for oral and maxillofacial surgery.

Authors:  Benjamas Apipan; Duangdee Rummasak; Natthamet Wongsirichat
Journal:  J Dent Anesth Pain Med       Date:  2016-12-31

Review 4.  Role of general anesthetic agents in postoperative nausea and vomiting: A review of literature.

Authors:  Shilpa Sunil Khanna; Muqthadir Siddiqui Mohammed Abdul; Urooj Fatima; Harshitha Garlapati; Mohd Abdul Qayyum; Sunil Kumar Gulia
Journal:  Natl J Maxillofac Surg       Date:  2022-06-15

5.  Efficacy of palonosetron in the management of postoperative nausea vomiting in oral and maxillofacial surgery.

Authors:  Keerthi Rapolu; Uday Kiran Uppada; Ramen Sinha; A V S S Subramanya Kumar
Journal:  Natl J Maxillofac Surg       Date:  2022-07-15
  5 in total

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