Literature DB >> 1968279

One-trial tolerance to the anxiolytic effects of chlordiazepoxide in the plus-maze.

S E File1.   

Abstract

Chlordiazepoxide (CDP 7.5 mg/kg) had a significant anxiolytic effect in rats tested on the plus-maze for the first time. On a second trial the control scores did not change, but those of the CDP group did and they no longer differed from controls. Rats previously tested undrugged or after flumazenil (4 mg/kg) also failed to show an anxiolytic response to CDP. Thus this phenomenon of one-trial tolerance depended on prior experience with the plus-maze. It also depended on CDP acting at the benzodiazepine receptors on trial 2, since the joint administration of CDP and flumazenil on trial 2 reversed the phenomenon.

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Year:  1990        PMID: 1968279     DOI: 10.1007/bf02244419

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  3 in total

1.  The use of a plus-maze to measure anxiety in the mouse.

Authors:  R G Lister
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

Review 2.  Tolerance to the behavioral actions of benzodiazepines.

Authors:  S E File
Journal:  Neurosci Biobehav Rev       Date:  1985       Impact factor: 8.989

3.  Anxiogenic effects in benzodiazepine withdrawal are linked to the development of tolerance.

Authors:  S E File; H A Baldwin; K Aranko
Journal:  Brain Res Bull       Date:  1987-11       Impact factor: 4.077

  3 in total
  31 in total

1.  Measuring anxiety- and locomotion-related behaviours in mice: a new way of using old tests.

Authors:  Leanne M Fraser; Richard E Brown; Ahmed Hussin; Mara Fontana; Ashley Whittaker; Timothy P O'Leary; Lauren Lederle; Andrew Holmes; André Ramos
Journal:  Psychopharmacology (Berl)       Date:  2010-05-08       Impact factor: 4.530

2.  Characterisation of the phenomenon of "one-trial tolerance" to the anxiolytic effect of chlordiazepoxide in the elevated plus-maze.

Authors:  S E File; P S Mabbutt; P K Hitchcott
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

3.  Effects of morphine on the plus-maze discriminative avoidance task: role of state-dependent learning.

Authors:  C L Patti; S R Kameda; R C Carvalho; A L Takatsu-Coleman; G B Lopez; S T Niigaki; V C Abílio; R Frussa-Filho; R H Silva
Journal:  Psychopharmacology (Berl)       Date:  2005-12-10       Impact factor: 4.530

4.  Scototaxis as anxiety-like behavior in fish.

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Journal:  Nat Protoc       Date:  2010-01-14       Impact factor: 13.491

5.  A five minute experience in the elevated plus-maze alters the state of the benzodiazepine receptor in the dorsal raphe nucleus.

Authors:  L E Gonzalez; S E File
Journal:  J Neurosci       Date:  1997-02-15       Impact factor: 6.167

6.  Fluoxetine administration to pregnant rats increases anxiety-related behavior in the offspring.

Authors:  Jocelien D A Olivier; A Vallès; Floor van Heesch; Anthonieke Afrasiab-Middelman; Janneke J P M Roelofs; Marloes Jonkers; Elke Joan Peeters; Gerdien A H Korte-Bouws; Jos P Dederen; Amanda J Kiliaan; Gerard J Martens; Dirk Schubert; Judith R Homberg
Journal:  Psychopharmacology (Berl)       Date:  2011-04-14       Impact factor: 4.530

7.  Female rats self-administer heroin by vapor inhalation.

Authors:  Arnold Gutierrez; Jacques D Nguyen; Kevin M Creehan; Michael A Taffe
Journal:  Pharmacol Biochem Behav       Date:  2020-10-24       Impact factor: 3.533

8.  "One-trial tolerance" to the anxiolytic actions of benzodiazepines in the elevated plus-maze, or the development of a phobic state?

Authors:  S E File; H Zangrossi
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

9.  Comparison of acute and chronic treatment of various serotonergic agents with those of diazepam and idazoxan in the rat elevated X-maze.

Authors:  I K Wright; M Heaton; N Upton; C A Marsden
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

10.  Behavioural assays to model cognitive and affective dimensions of depression and anxiety in rats.

Authors:  M D S Lapiz-Bluhm; C O Bondi; J Doyen; G A Rodriguez; T Bédard-Arana; D A Morilak
Journal:  J Neuroendocrinol       Date:  2008-07-30       Impact factor: 3.627

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