Literature DB >> 19682338

A novel rapid and effective donor arm disinfection method.

Carl McDonald1, Siobhan McGuane, Julia Thomas, Stephen Hartley, Steve Robbins, Anjana Roy, Neville Verlander, John Barbara.   

Abstract

BACKGROUND: The aim of the study was to derive a donor arm disinfection technique that was rapid, but with a disinfection efficacy equivalent to a previous "best-practice" technique. This method consisted of a two-stage procedure with an initial application of 70% isopropyl alcohol and then 2% tincture of iodine (IATI). The total time for the IATI method was 2 minutes in duration. A rapid technique (1 min in duration) was needed to obviate potential problems due to increased donor waiting time, had the IATI method been implemented at blood donation sessions. STUDY DESIGN AND METHODS: A direct swabbing and plating technique was used to enumerate bacteria present before and after disinfection. In total, seven methods were evaluated.
RESULTS: The chlorhexidine/alcohol applicator (CAA) disinfection device containing 1.5 mL of 2% chlorhexidine gluconate and 70% isopropyl alcohol (99.91% reduction; confidence limits, 99.55%, 99.98%) was shown to have equivalent disinfection efficacy as the IATI method (99.89% reduction; confidence limits, 99.36%, 99.98%; p = 0.86). Procedural time for the 1.5-mL CAA method was 1 minute thereby avoiding potential problems of increased donor waiting time, inherent in the IATI 2-minute procedure at blood donation sessions.
CONCLUSIONS: The 1.5-mL CAA disinfection method offers blood services a rapid and effective donor arm disinfection procedure. In 2006, the 1.5-mL CAA procedure was implemented throughout the entire English blood service for all donations.

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Year:  2009        PMID: 19682338     DOI: 10.1111/j.1537-2995.2009.02332.x

Source DB:  PubMed          Journal:  Transfusion        ISSN: 0041-1132            Impact factor:   3.157


  5 in total

1.  Interventions Implemented to Reduce the Risk of Transmission of Bacteria by Transfusion in the English National Blood Service.

Authors:  Carl P McDonald
Journal:  Transfus Med Hemother       Date:  2011-07-15       Impact factor: 3.747

Review 2.  Skin preparation with alcohol versus alcohol followed by any antiseptic for preventing bacteraemia or contamination of blood for transfusion.

Authors:  Joan Webster; Sally E M Bell-Syer; Ruth Foxlee
Journal:  Cochrane Database Syst Rev       Date:  2015-02-12

3.  Evaluation of the Role of Novel Aprotic Dimethyl Sulfoxide in Cutaneous Antisepsis Protocols Prior to Blood Donor Phlebotomy with Isopropyl Alcohol, Povidone Iodine or Chlorhexidine.

Authors:  Suchet Sachdev; Nandini Sethuraman; Vikas Gautam; Deepak Pahwa; Anuradha Kalra; Ratti Ram Sharma; Neelam Marwaha; Pallab Ray
Journal:  Indian J Hematol Blood Transfus       Date:  2017-04-20       Impact factor: 0.900

4.  Transfusion and risk of infection in Canada: Update 2012.

Authors:  Noni E Macdonald; Sheila F O'Brien; Gilles Delage
Journal:  Paediatr Child Health       Date:  2012-12       Impact factor: 2.253

5.  Study of the hormetic effect of disinfectants chlorhexidine, povidone iodine and benzalkonium chloride.

Authors:  L Morales-Fernández; M Fernández-Crehuet; M Espigares; E Moreno; E Espigares
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-07-27       Impact factor: 3.267

  5 in total

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