Literature DB >> 19681890

Robert F. Furchgott, Nobel laureate (1916-2009)--a personal reflection.

William Martin.   

Abstract

Robert F. Furchgott, pharmacologist and joint winner of the Nobel Prize for Medicine or Physiology (1998) died on the 12th of May 2009 aged 92. By unlocking the astonishingly diverse biological actions of nitric oxide, Furchgott leaves behind a rich legacy that has both revolutionized our understanding of human physiology and stimulated new and exciting opportunities for drug development in a wide range of pathological conditions. In this article, William Martin, who worked with Furchgott for 2 years (1983-1985), following the exciting discovery of endothelium-derived relaxing factor/nitric oxide, pays tribute to his close friend and colleague.

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Year:  2009        PMID: 19681890      PMCID: PMC2765585          DOI: 10.1111/j.1476-5381.2009.00418.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  37 in total

1.  Phosphodiesterase inhibitors induce endothelium-dependent relaxation of rat and rabbit aorta by potentiating the effects of spontaneously released endothelium-derived relaxing factor.

Authors:  W Martin; R F Furchgott; G M Villani; D Jothianandan
Journal:  J Pharmacol Exp Ther       Date:  1986-05       Impact factor: 4.030

2.  Blockade of endothelium-dependent vasodilation by hemoglobin: a possible factor in vasospasm associated with hemorrhage.

Authors:  R F Furchgott; W Martin; P D Cherry
Journal:  Adv Prostaglandin Thromboxane Leukot Res       Date:  1985

3.  Blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation of rabbit aorta by certain ferrous hemoproteins.

Authors:  W Martin; G M Villani; D Jothianandan; R F Furchgott
Journal:  J Pharmacol Exp Ther       Date:  1985-06       Impact factor: 4.030

4.  Block of some non-adrenergic inhibitory responses of smooth muscle by a substance from haemolysed erythrocytes.

Authors:  A Bowman; J S Gillespie
Journal:  J Physiol       Date:  1982-07       Impact factor: 5.182

5.  Some physical and chemical properties of the smooth muscle inhibitory factor in extracts of the bovine retractor penis muscle.

Authors:  J S Gillespie; J C Hunter; W Martin
Journal:  J Physiol       Date:  1981-06       Impact factor: 5.182

6.  Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta.

Authors:  W Martin; G M Villani; D Jothianandan; R F Furchgott
Journal:  J Pharmacol Exp Ther       Date:  1985-03       Impact factor: 4.030

7.  Depression of contractile responses in rat aorta by spontaneously released endothelium-derived relaxing factor.

Authors:  W Martin; R F Furchgott; G M Villani; D Jothianandan
Journal:  J Pharmacol Exp Ther       Date:  1986-05       Impact factor: 4.030

8.  Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor.

Authors:  R J Gryglewski; R M Palmer; S Moncada
Journal:  Nature       Date:  1986 Apr 3-9       Impact factor: 49.962

9.  Cyclic GMP mediates neurogenic relaxation in the bovine retractor penis muscle.

Authors:  A Bowman; A H Drummond
Journal:  Br J Pharmacol       Date:  1984-04       Impact factor: 8.739

10.  Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.

Authors:  R M Rapoport; F Murad
Journal:  Circ Res       Date:  1983-03       Impact factor: 17.367

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  3 in total

1.  Robert F. Furchgott and his heritage: endothelial vasomotor control.

Authors:  Bernd Nilius; Dragomir N Serban; Paul M Vanhoutte
Journal:  Pflugers Arch       Date:  2010-05       Impact factor: 3.657

2.  The Use of Low Level Laser Therapy (LLLT) For Musculoskeletal Pain.

Authors:  Howard B Cotler; Roberta T Chow; Michael R Hamblin; James Carroll
Journal:  MOJ Orthop Rheumatol       Date:  2015-06-09

Review 3.  Implications of Oxidative and Nitrosative Post-Translational Modifications in Therapeutic Strategies against Reperfusion Damage.

Authors:  Mabel Buelna-Chontal; Wylly R García-Niño; Alejandro Silva-Palacios; Cristina Enríquez-Cortina; Cecilia Zazueta
Journal:  Antioxidants (Basel)       Date:  2021-05-08
  3 in total

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