Literature DB >> 26858986

The Use of Low Level Laser Therapy (LLLT) For Musculoskeletal Pain.

Howard B Cotler1, Roberta T Chow2, Michael R Hamblin3, James Carroll4.   

Abstract

Pain is the most common reason for physician consultation in the United States. One out of three Americans is affected by chronic pain annually. The number one reason for missed work or school days is musculoskeletal pain. Currently accepted therapies consist of non-steroidal anti-inflammatory drugs, steroid injections, opiate pain medications and surgery, each of which carries their own specific risk profiles. What is needed are effective treatments for pain which have an acceptably low risk-profile. For over forty years, low level laser (light) therapy (LLLT) and LED (light emitting diode) therapy (also known as photobiomodulation) has been shown to reduce inflammation and edema, induce analgesia, and promote healing in a range of musculoskeletal pathologies. The purpose of this paper is to review the use of LLLT for pain, the biochemical mechanisms of action, the dose response curves, and how LLLT may be employed by orthopedic surgeons to improve outcomes and reduce adverse events. With the predicted epidemic of chronic pain in developed countries, it is imperative to validate cost-effective and safe techniques for managing painful conditions which would allow people to live active and productive lives. Moreover the acceptance of LLLT (which is currently being used by many specialties around the world) into the armamentarium of the American health care provider would allow for additional treatment options for patients. A new cost-effective therapy for pain could elevate quality of life while reducing financial strains.

Entities:  

Keywords:  Injury repair; Low level laser therapy; Musculoskeletal; Pain; Photobiomodulation

Year:  2015        PMID: 26858986      PMCID: PMC4743666          DOI: 10.15406/mojor.2015.02.00068

Source DB:  PubMed          Journal:  MOJ Orthop Rheumatol        ISSN: 2374-6939


  84 in total

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Authors:  R Lubart; Y Wollman; H Friedmann; S Rochkind; I Laulicht
Journal:  J Photochem Photobiol B       Date:  1992-02-28       Impact factor: 6.252

2.  Low-level laser treatment can reduce edema in second degree ankle sprains.

Authors:  Apostolos Stergioulas
Journal:  J Clin Laser Med Surg       Date:  2004-04

3.  830 nm laser irradiation induces varicosity formation, reduces mitochondrial membrane potential and blocks fast axonal flow in small and medium diameter rat dorsal root ganglion neurons: implications for the analgesic effects of 830 nm laser.

Authors:  Roberta T Chow; Monique A David; Patricia J Armati
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4.  Low-level laser therapy with a wrist splint to treat carpal tunnel syndrome: a double-blinded randomized controlled trial.

Authors:  Yupadee Fusakul; Thanyaporn Aranyavalai; Phongphitch Saensri; Satit Thiengwittayaporn
Journal:  Lasers Med Sci       Date:  2014-01-30       Impact factor: 3.161

5.  Low-level laser therapy reduces time to ambulation in dogs after hemilaminectomy: a preliminary study.

Authors:  W E Draper; T A Schubert; R M Clemmons; S A Miles
Journal:  J Small Anim Pract       Date:  2012-07-11       Impact factor: 1.522

6.  Low energy visible light induces reactive oxygen species generation and stimulates an increase of intracellular calcium concentration in cardiac cells.

Authors:  Ronit Lavi; Asher Shainberg; Harry Friedmann; Vladimir Shneyvays; Ophra Rickover; Maor Eichler; Doron Kaplan; Rachel Lubart
Journal:  J Biol Chem       Date:  2003-07-07       Impact factor: 5.157

7.  Low-level laser reduces the production of TNF-α, IFN-γ, and IL-10 induced by OVA.

Authors:  Rodrigo G Oliveira; Ana P Ferreira; Andréa J Côrtes; Beatriz J Vieira Aarestrup; Luis C Andrade; Fernando M Aarestrup
Journal:  Lasers Med Sci       Date:  2013-01-22       Impact factor: 3.161

8.  Perceptual correlates of nociceptive long-term potentiation and long-term depression in humans.

Authors:  Thomas Klein; Walter Magerl; Hanns-Christian Hopf; Jürgen Sandkühler; Rolf-Detlef Treede
Journal:  J Neurosci       Date:  2004-01-28       Impact factor: 6.167

9.  Superpulsed (Ga-As, 904 nm) low-level laser therapy (LLLT) attenuates inflammatory response and enhances healing of burn wounds.

Authors:  Asheesh Gupta; Gaurav K Keshri; Anju Yadav; Shefali Gola; Satish Chauhan; Ashok K Salhan; Shashi Bala Singh
Journal:  J Biophotonics       Date:  2014-09-10       Impact factor: 3.207

10.  Effects of laser irradiation at different wavelengths (660, 810, 980, and 1,064 nm) on mucositis in an animal model of wound healing.

Authors:  Aslihan Usumez; Beyhan Cengiz; Serdar Oztuzcu; Tuncer Demir; Mutan Hamdi Aras; Norbert Gutknecht
Journal:  Lasers Med Sci       Date:  2013-05-01       Impact factor: 3.161

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  48 in total

1.  Light-Emitting Diode Phototherapy Reduces Nocifensive Behavior Induced by Thermal and Chemical Noxious Stimuli in Mice: Evidence for the Involvement of Capsaicin-Sensitive Central Afferent Fibers.

Authors:  Glauce Regina Pigatto; Igor Santos Coelho; Rosane Schenkel Aquino; Liliane Freitas Bauermann; Adair Roberto Soares Santos
Journal:  Mol Neurobiol       Date:  2016-04-07       Impact factor: 5.590

Review 2.  Laser Acupuncture: A Concise Review.

Authors:  Tony Y Chon; Molly J Mallory; Juan Yang; Sara E Bublitz; Alexander Do; Peter T Dorsher
Journal:  Med Acupunct       Date:  2019-06-17

3.  Photobiomodulation therapy at different wavelength impacts on retinoid acid-dependent SH-SY5Y differentiation.

Authors:  Luisa Zupin; Fulvio Celsi; Giulia Ottaviani; Sergio Crovella
Journal:  Lasers Med Sci       Date:  2019-03-25       Impact factor: 3.161

4.  Low-level laser therapy in 3D cell culture model using gingival fibroblasts.

Authors:  Fernanda G Basso; Diana G Soares; Carlos Alberto de Souza Costa; Josimeri Hebling
Journal:  Lasers Med Sci       Date:  2016-04-28       Impact factor: 3.161

Review 5.  Modulatory effect of photobiomodulation on stem cell epigenetic memory: a highlight on differentiation capacity.

Authors:  Arezoo Rezaie Nezhad Zamani; Shirin Saberianpour; Mohammad Hossein Geranmayeh; Farhad Bani; Leila Haghighi; Reza Rahbarghazi
Journal:  Lasers Med Sci       Date:  2019-09-07       Impact factor: 3.161

6.  Effect of photobiomodulation therapy (808 nm) in the control of neuropathic pain in mice.

Authors:  Ana Laura Martins de Andrade; Paulo Sérgio Bossini; Azair Liane Matos do Canto De Souza; Ariane Dutra Sanchez; Nivaldo Antonio Parizotto
Journal:  Lasers Med Sci       Date:  2017-03-10       Impact factor: 3.161

7.  The effect of a single irradiation of low-level laser on nipple pain in breastfeeding women: a randomized controlled trial.

Authors:  Bárbara Tideman Sartorio Camargo; Kelly Pereira Coca; Lisa Helen Amir; Luciana Corrêa; Ana Cecília Corrêa Aranha; Karla Oliveira Marcacine; Érika de Sá Vieira Abuchaim; Ana Cristina Freitas de Vilhena Abrão
Journal:  Lasers Med Sci       Date:  2019-04-27       Impact factor: 3.161

Review 8.  Laser Light Therapy in Inflammatory, Musculoskeletal, and Autoimmune Disease.

Authors:  Victoria A Wickenheisser; Emilia Marta Zywot; Emily Mary Rabjohns; Hyun Ho Lee; David S Lawrence; Teresa Kathleen Tarrant
Journal:  Curr Allergy Asthma Rep       Date:  2019-07-02       Impact factor: 4.806

Review 9.  The Beneficial Effects of High-Intensity Laser Therapy and Co-Interventions on Musculoskeletal Pain Management: A Systematic Review.

Authors:  Kamran Ezzati; E-Liisa Laakso; Amir Salari; Anahita Hasannejad; Reza Fekrazad; Arash Aris
Journal:  J Lasers Med Sci       Date:  2020-01-18

10.  Laser treatment of synovial inflammatory process in experimentally induced microcrystalline arthritis in Wistar rats.

Authors:  Débora Mara Fortes Bartoli; Airton Luiz Felizatti; Fernando Russo Costa do Bomfim; Julia Leme Bovo; Andrea Aparecida de Aro; Maria Esméria Corezzola do Amaral; Marcelo Augusto Marretto Esquisatto
Journal:  Lasers Med Sci       Date:  2020-06-10       Impact factor: 3.161

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