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Literature DB >> 19679771

An acidic matrix protein, Pif, is a key macromolecule for nacre formation.

Michio Suzuki¹, Kazuko Saruwatari, Toshihiro Kogure, Yuya Yamamoto, Tatsuya Nishimura, Takashi Kato, Hiromichi Nagasawa.

Abstract

The mollusk shell is a hard tissue consisting of calcium carbonate crystals and an organic matrix. The nacre of the shell is characterized by a stacked compartment structure with a uniformly oriented c axis of aragonite crystals in each compartment. Using a calcium carbonate-binding assay, we identified an acidic matrix protein, Pif, in the pearl oyster Pinctada fucata that specifically binds to aragonite crystals. The Pif complementary DNA (cDNA) encoded a precursor protein, which was posttranslationally cleaved to produce Pif 97 and Pif 80. The results from immunolocalization, a knockdown experiment that used RNA interference, and in vitro calcium carbonate crystallization studies strongly indicate that Pif regulates nacre formation.

Entities: Chemical Species

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Year: 2009 PMID： 19679771 DOI： 10.1126/science.1173793

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

143 in total

1. Proteomic strategy for identifying mollusc shell proteins using mild chemical degradation and trypsin digestion of insoluble organic shell matrix: a pilot study on Haliotis tuberculata.

Authors: Laurent Bédouet; Arul Marie; Sophie Berland; Benjamin Marie; Stéphanie Auzoux-Bordenave; Frédéric Marin; Christian Milet
Journal: Mar Biotechnol (NY) Date: 2011-12-13 Impact factor: 3.619

2. A new method to extract matrix proteins directly from the secretion of the mollusk mantle and the role of these proteins in shell biomineralization.

Authors: Xiaojun Liu; Chang Liu; Lei Chen; Juan Sun; Yujuan Zhou; Qi Li; Guilan Zheng; Guiyou Zhang; Hongzhong Wang; Liping Xie; Rongqing Zhang
Journal: Mar Biotechnol (NY) Date: 2011-01-29 Impact factor: 3.619

3. Phase transitions in biogenic amorphous calcium carbonate.

Authors: Yutao U T Gong; Christopher E Killian; Ian C Olson; Narayana P Appathurai; Audra L Amasino; Michael C Martin; Liam J Holt; Fred H Wilt; P U P A Gilbert
Journal: Proc Natl Acad Sci U S A Date: 2012-04-04 Impact factor: 11.205

4. Functional characterization and molecular mechanism exploration of three granulin epithelin precursor splice variants in biomineralization of the pearl oyster Pinctada fucata.

Authors: Mi Zhao; Maoxian He; Xiande Huang; Qi Wang; Yu Shi
Journal: Mol Genet Genomics Date: 2015-09-20 Impact factor: 3.291

5. A basic protein, N25, from a mollusk modifies calcium carbonate morphology and shell biomineralization.

Authors: Dong Yang; Yi Yan; Xue Yang; Jun Liu; Guilan Zheng; Liping Xie; Rongqing Zhang
Journal: J Biol Chem Date: 2019-04-09 Impact factor: 5.157

6. Accelerating the design of biomimetic materials by integrating RNA-seq with proteomics and materials science.

Authors: Paul A Guerette; Shawn Hoon; Yiqi Seow; Manfred Raida; Admir Masic; Fong T Wong; Vincent H B Ho; Kiat Whye Kong; Melik C Demirel; Abdon Pena-Francesch; Shahrouz Amini; Gavin Z Tay; Dawei Ding; Ali Miserez
Journal: Nat Biotechnol Date: 2013-09-08 Impact factor: 54.908

An acidic matrix protein, Pif, is a key macromolecule for nacre formation.

1. Proteomic strategy for identifying mollusc shell proteins using mild chemical degradation and trypsin digestion of insoluble organic shell matrix: a pilot study on Haliotis tuberculata.

2. A new method to extract matrix proteins directly from the secretion of the mollusk mantle and the role of these proteins in shell biomineralization.

3. Phase transitions in biogenic amorphous calcium carbonate.

4. Functional characterization and molecular mechanism exploration of three granulin epithelin precursor splice variants in biomineralization of the pearl oyster Pinctada fucata.

5. A basic protein, N25, from a mollusk modifies calcium carbonate morphology and shell biomineralization.

6. Accelerating the design of biomimetic materials by integrating RNA-seq with proteomics and materials science.

7. Pearl Sac Gene Expression Profiles Associated With Pearl Attributes in the Silver-Lip Pearl Oyster, Pinctada maxima.

8. Molecular evolution of mollusc shell proteins: insights from proteomic analysis of the edible mussel Mytilus.

9. Glycolytic intermediates induce amorphous calcium carbonate formation in crustaceans.

10. Transcriptional regulation of the matrix protein Shematrin-2 during shell formation in pearl oyster.