Literature DB >> 1967417

Parathyroid-hormone-related protein in tumours associated with hypercalcaemia.

D A Heath1, P V Senior, J M Varley, F Beck.   

Abstract

Parathyroid-hormone-related protein (PTHrP) messenger RNA was identified by in-situ hybridisation in seven tumours complicated by hypercalcaemia. In addition, among samples from normocalcaemic patients, it was commonly found in tumours of types frequently complicated by hypercalcaemia but was not found in tumours that are rarely complicated by hypercalcaemia. Positive results were obtained with both freshly frozen and archive paraffin-embedded material. These findings support the view that PTHrP is a common cause of hypercalcaemia in malignant disorders.

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Year:  1990        PMID： 1967417     DOI： 10.1016/0140-6736(90)90537-f

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  10 in total

Review 1.  In situ hybridisation in perspective.

Authors:  A Warford; I Lauder
Journal:  J Clin Pathol       Date:  1991-03       Impact factor: 3.411

2.  Reverse transcriptase/polymerase chain reaction analysis of parathyroid hormone-related protein for the detection of tumor cell dissemination in the peripheral blood and bone marrow of patients with breast cancer.

Authors:  G G Wulf; B Jürgens; T Liersch; W Gatzemeier; H Rauschecker; C Buske; M Hüfner; W Hiddemann; B Wörmann
Journal:  J Cancer Res Clin Oncol       Date:  1997       Impact factor: 4.553

3.  Pancreatic neuroendocrine cell tumor secreting parathyroid hormone-related protein and gastrin: Report of a case.

Authors:  Yoshifumi Morita; Shohachi Suzuki; Takanori Sakaguchi; Kosuke Oishi; Atsushi Suzuki; Kazuhiko Fukumoto; Keisuke Inaba; Satoshi Baba; Yasuo Takehara; Hiroyuki Konno
Journal:  Surg Today       Date:  2010-11-26       Impact factor: 2.549

4.  Parathyroid hormone related protein in hypercalcaemia of Hodgkin's disease.

Authors:  J Bolo-Deoku; S Basu; S Lakhani; F Dunne; W A Ratcliffe; M Clarke; J L Barron
Journal:  J Clin Pathol       Date:  1992-06       Impact factor: 3.411

5.  Parathyroid hormone-related peptide in pancreatic neuroendocrine tumours associated with hypercalcaemia.

Authors:  I M Papazachariou; I T Virlos; R C Williamson
Journal:  HPB (Oxford)       Date:  2001       Impact factor: 3.647

6.  Malignant phaeochromocytoma and hypercalcaemia.

Authors:  J A Bridgewater; W A Ratcliffe; N J Bundred; C W Owens
Journal:  Postgrad Med J       Date:  1993-01       Impact factor: 2.401

7.  Parathyroid hormone related protein and interleukin-6 mRNA expression in larynx and renal cell carcinomas from normocalcaemic and hypercalcaemic patients.

Authors:  D H Schweitzer; I L Boxman; C W Löwik; J H van Krieken; M G Weissglas; R J Baatenburg de Jong; S E Papapoulos
Journal:  J Clin Pathol       Date:  1995-10       Impact factor: 3.411

8.  Elevated serum parathyroid hormone related protein and 1,25-dihydroxycholecalciferol in hypercalcaemia associated with adult T-cell leukaemia-lymphoma.

Authors:  S R Johnston; P J Hammond
Journal:  Postgrad Med J       Date:  1992-09       Impact factor: 2.401

9.  Parathyroid hormone-related protein as a tumour marker in humoral hypercalcaemia associated with occult malignancy.

Authors:  A C Hutchesson; F Dunne; N J Bundred; H Gee; W A Ratcliffe
Journal:  Postgrad Med J       Date:  1993-08       Impact factor: 2.401

10.  The expression of the gene coding for parathyroid hormone-related protein (PTHrP) during tooth development in the rat.

Authors:  F Beck; J Tucci; A Russell; P V Senior; M W Ferguson
Journal:  Cell Tissue Res       Date:  1995-05       Impact factor: 5.249
  10 in total

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