Literature DB >> 19672675

Effect of Gastrodia elata on tumor necrosis factor-alpha-induced matrix metalloproteinase activity in endothelial cells.

Yun Jung Lee1, Sun Mi Hwang, Dae Gill Kang, Jin Sook Kim, Ho Sub Lee.   

Abstract

The aim of the present study was to investigate whether an ethanol extract of Gastrodia elata (EGE) rhizome, a traditional Korean herbal medical food, suppresses the endothelial extracellular matrix degradation induced by tumor necrosis factor (TNF)-alpha. Gelatin zymography results showed that pretreatment with EGE to human umbilical vein endothelial cells (HUVEC) decreased TNF-alpha-induced increase of matrix metalloproteinase (MMP)-2/-9 activities in the range of 1-50 microg/ml. Real-time qRT-PCR results also revealed that TNF-alpha-induced MMP-2/-9 mRNA expression levels were attenuated by pretreatment with EGE. These results provide new insights into the pathophysiological mechanisms for the anti-atherosclerotic properties of EGE in vascular diseases.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19672675     DOI： 10.1007/s11418-009-0352-6

Source DB:  PubMed          Journal:  J Nat Med        ISSN： 1340-3443            Impact factor:   2.343


  14 in total

Review 1.  Vascular inflammation as a therapeutic target for prevention of cardiovascular disease.

Authors:  Luther T Clark
Journal:  Curr Atheroscler Rep       Date:  2002-03       Impact factor: 5.113

2.  Matrix metalloproteinase hypothesis of plaque rupture: players keep piling up but questions remain.

Authors:  P K Shah; Z S Galis
Journal:  Circulation       Date:  2001-10-16       Impact factor: 29.690

3.  Opposite effects of high glucose on MMP-2 and TIMP-2 in human endothelial cells.

Authors:  Feng M Ho; Shing H Liu; Wan W Lin; Chiau S Liau
Journal:  J Cell Biochem       Date:  2007-05-15       Impact factor: 4.429

4.  CD16+ monocytes produce IL-6, CCL2, and matrix metalloproteinase-9 upon interaction with CX3CL1-expressing endothelial cells.

Authors:  Petronela Ancuta; Jianbin Wang; Dana Gabuzda
Journal:  J Leukoc Biol       Date:  2006-11       Impact factor: 4.962

5.  Collagenase activity in anterior cruciate ligament: protective role of the synovial sheath.

Authors:  D Amiel; E Billings; F L Harwood
Journal:  J Appl Physiol (1985)       Date:  1990-09

6.  High glucose and Nepsilon-(carboxymethyl) lysine bovine serum albumin modulate release of matrix metalloproteinases in cultured human endothelial cells.

Authors:  Sedegheh Gharagozlian; Tore Henriksen; Svein Olav Kolset
Journal:  Eur J Nutr       Date:  2006-05-16       Impact factor: 5.614

7.  Anti-inflammatory effect of Gastrodia elata rhizome in human umbilical vein endothelial cells.

Authors:  Sun Mi Hwang; Yun Jung Lee; Dae Gill Kang; Ho Sub Lee
Journal:  Am J Chin Med       Date:  2009       Impact factor: 4.667

8.  Sophorae radix extract inhibits high glucose-induced vascular cell adhesion molecule-1 up-regulation on endothelial cell line.

Authors:  Kang-Beom Kwon; Eun-Kyung Kim; Jung-Gook Lim; Byung-Cheul Shin; Yung-Sun Song; Eun-A Seo; Ki-Young Ahn; Bong-Keun Song; Do-Gon Ryu
Journal:  Clin Chim Acta       Date:  2004-10       Impact factor: 3.786

9.  Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.

Authors:  Z S Galis; G K Sukhova; M W Lark; P Libby
Journal:  J Clin Invest       Date:  1994-12       Impact factor: 14.808

10.  Increased type-IV collagenase (MMP-2 and MMP-9) activity following preoperative radiotherapy in rectal cancer.

Authors:  A Kumar; H M Collins; J H Scholefield; S A Watson
Journal:  Br J Cancer       Date:  2000-02       Impact factor: 7.640
View more
  8 in total

1.  Propofol attenuates TNF-α-induced MMP-9 expression in human cerebral microvascular endothelial cells by inhibiting Ca2+/CAMK II/ERK/NF-κB signaling pathway.

Authors:  Xiao-Wei Ding; Xia Sun; Xue-Fang Shen; Yan Lu; Jia-Qiang Wang; Zhi-Rong Sun; Chang-Hong Miao; Jia-Wei Chen
Journal:  Acta Pharmacol Sin       Date:  2019-06-24       Impact factor: 6.150

2.  Vascular protective role of vitexicarpin isolated from Vitex rotundifolia in human umbilical vein endothelial cells.

Authors:  So Min Lee; Yun Jung Lee; Youn Chul Kim; Jin Sook Kim; Dae Gill Kang; Ho Sub Lee
Journal:  Inflammation       Date:  2012-04       Impact factor: 4.092

3.  Gastrodia elata Ameliorates High-Fructose Diet-Induced Lipid Metabolism and Endothelial Dysfunction.

Authors:  Min Chul Kho; Yun Jung Lee; Jeong Dan Cha; Kyung Min Choi; Dae Gill Kang; Ho Sub Lee
Journal:  Evid Based Complement Alternat Med       Date:  2014-02-26       Impact factor: 2.629

Review 4.  Gastrodiae Rhizoma (tiān má): a review of biological activity and antidepressant mechanisms.

Authors:  Pei-Ju Chen; Lee-Yan Sheen
Journal:  J Tradit Complement Med       Date:  2011-10

5.  Lipingshu capsule improves atherosclerosis associated with lipid regulation and inflammation inhibition in apolipoprotein E-deficient mice.

Authors:  Jiqu Xu; Congcong Ma; Meng Chen; Shuang Rong; Hui Gao; Zumeng Xia; Fenghong Huang
Journal:  Lipids Health Dis       Date:  2018-07-31       Impact factor: 3.876

6.  Optimal Extraction Study of Gastrodin-Type Components from Gastrodia Elata Tubers by Response Surface Design with Integrated Phytochemical and Bioactivity Evaluation.

Authors:  Minhui Hu; Hui Yan; Yuanyuan Fu; Yulan Jiang; Weifeng Yao; Sheng Yu; Li Zhang; Qinan Wu; Anwei Ding; Mingqiu Shan
Journal:  Molecules       Date:  2019-02-02       Impact factor: 4.411

7.  Membrane type 1-matrix metalloproteinase/Akt signaling axis modulates TNF-α-induced procoagulant activity and apoptosis in endothelial cells.

Authors:  Hiroshi Ohkawara; Toshiyuki Ishibashi; Koichi Sugimoto; Kazuhiko Ikeda; Kazuei Ogawa; Yasuchika Takeishi
Journal:  PLoS One       Date:  2014-08-27       Impact factor: 3.240

8.  Extraction, Characterization and Immunological Activity of Polysaccharides from Rhizoma gastrodiae.

Authors:  Juncheng Chen; Shan Tian; Xiaoying Shu; Hongtao Du; Na Li; Junru Wang
Journal:  Int J Mol Sci       Date:  2016-06-25       Impact factor: 5.923
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.